"Research Assistant I Lab"

Job Summary

The Hotamışlıgil Lab explores the fundamental molecular mechanisms that cause obesity- or aging-related disease clusters including diabetes, liver and pulmonary disease, and atherosclerosis with the aim of developing novel therapeutic interventions to treat these diseases. The lab has made important contributions to the fields of "metabolism" and especially "immunometabolism", studying the interactions between metabolic and immune responses as critical drivers of numerous chronic diseases. In the last decade, we have approached immunometabolism in two major paths: organelle homeostasis and lipid metabolism. Using biochemical, genetic, and physiological studies, we aim to find novel pathways and preventive, therapeutic solutions to today’s greatest threats to global human health. The environment in our laboratory is collegial, supportive, and diverse. One of the greatest powers of science is its ability to unite people, where all people can work together for a common purpose. This is most evident in our lab where we come together to tackle challenging questions and dream to make a positive impact on human life. Our laboratory can be found at https://www.gsh.sph.harvard.edu.

We are looking for a Research Assistant (RA) who is enthusiastic and excited about biomedical science and the work we do in our lab, and who wants to make a strong scientific contribution to our research. This Research Assistant will work with molecules, cells, and molecular biology platforms as well as perform physiology experiments in genetically engineered mouse models, including studies implementing advanced physiological instrumentation and surgeries. It is an opportunity to learn advanced techniques in molecular biology, protein and RNA purification and analysis, mammalian tissue culture, biochemical assays, immunostaining, and microscopy. The RA will follow up experiments by organizing, processing, and reporting data. RAs are expected to be fully engaged in the intellectual activities of the lab and actively participate in lab meetings and discussions. We work as a team and look for strong and positive team spirit in all our members.

Job-Specific Responsibilities

The primary responsibilities of the Research Assistant include, but are not limited to:

• Performing cell culture and molecular biology experiments.
• Performing mouse metabolic physiology experiments.
• Maintaining mouse colonies, including breeding and genotyping.
• Processing tissue, blood, and cell culture samples for protein, RNA, and metabolite analysis.
• Analysis, interpretation, and reporting of data.
• Participation and intellectual contribution to lab meetings, journal clubs, and data discussions.
• Performs other duties as assigned

PLEASE NOTE: The finalist for this position will be required to pass an occupational health screen. There may be times when, due to technical aspects of an experiment, the RA will be required to work outside of normal working hours (such as on evenings, weekends, and holidays).

Physical Requirements

• Lifting 25 pounds, climbing a three-step ladder, and handling live mice

Qualifications

Basic Qualifications

• 1+ year of relevant experience required; a combination of education and experience may be considered

Additional Qualifications and Skills

• Bachelor's degree or equivalent training and experience; preferably in biological sciences
• Experience in basic molecular and cellular biology techniques required.
• Scientific curiosity, high level of initiative and motivation; ability to work independently and with a team preferred. Excellent communication, organization, time management, and record-keeping skills. Strong organizational skills and experience in handling sensitive and confidential information. Experience in performing animal studies preferred.
• Two or more years experience in a molecular biology laboratory at the bench
• Exposure to or experience in basic molecular and cellular biology techniques strongly preferred
• Understanding of the necessity for proper handling of pre-published confidential research data
• Demonstrated high level of initiative and motivation
• Experience working independently and with a team
• Proven excellence in communication, organization, time management, and record-keeping skills
• Strong organizational skills

Additional Information

• Appointment End Date: Two years from date of hire
• Standard Hours/Schedule: 35 hours per week
• Visa Sponsorship Information: Harvard University is unable to provide visa sponsorship for this position
• Pre-Employment Screening: Identity, Criminal

Work Format Details
This position has been determined by school or unit leaders that all duties and responsibilities must be performed at a Harvard or Harvard-designated location. Certain visa types may limit work location. Individuals must meet work location sponsorship requirements prior to employment.

Salary Grade and Ranges
This position is salary grade level 052. Please visit Harvard's Salary Ranges to view the corresponding salary range and related information.