"Research Assistant"

Position Summary

The Center for Translational & Computational Neuroimmunology (CTCN), in the Department of Neurology at Columbia University Irving Medical Center (CUIMC) is a hub for large-scale translational human studies that integrate rigorous application of advanced laboratory techniques with cutting-edge computational methods. The CTCN includes a Neuroimmunology Core which specializes in the optimization and deployment of novel experimental platforms to support the projects of CTCN investigators and collaborators. We are currently seeking a Research Assistant to join our research effort in the CNS tissue-based profiling. We are deploying traditional (immunohistochemistry/fluorescence, in situ hybridization) and emerging spatial transcriptomic technologies coupled to a robust image capture and semi-automated image segmentation pipeline to enable the large-scale projects that are currently funded.

Responsibilities

Histology Assays (80%)

• Perform histology techniques, including sectioning of paraffin-embedded and frozen tissue using a microtome or cryostat.
• Independently carry out large-scale tissue staining projects with high accuracy and consistency.
• Apply established laboratory procedures and techniques relevant to histological analysis.
• Maintain accurate records of experimental procedures and results; analyze and present findings to the research team.

Biobank Support (20%)

• Process and prepare biospecimens (e.g., blood, serum, plasma, DNA, CSF) according to research protocols and ensure proper labeling and storage.
• Coordinate and execute the shipment of biospecimens in compliance with institutional and regulatory guidelines.
• Enter and update data in relevant databases accurately; perform assigned quality assurance tasks to ensure timely and accurate data transmission.

Minimum Qualifications

Bachelor’s Degree and at least 1.5 years of related experience or equivalent in education, training, and experience

Preferred Qualifications

Experience working with RNA and protein staining is strongly preferred. Experience handling human clinical biopsies or animal tissues is preferred. Bachelor's degree in Life Sciences or related scientific field required. 2-4 Years Related Work Experience preferred. Basic understanding of molecular biology and analytical techniques including PCR, RT-qPCR, molecular cloning, nucleic acid isolation and manipulation. Ability to learn new skills and knowledge on the job and productively deliver high-quality results. Attention to detail and maintenance of good scientific records. Excellent organizational and documentation skills.

Other Requirements

Work effectively in a team environment.