Research Associate (Fixed Term)

University of Cambridge - Department of Medicine

Our group has a long-standing interest in immunology and mucosal immunology. We have contributed to the elucidation of ER stress and autophagy mechanisms in the intestinal epithelium. Departing from human genetics, we also discovered an unprecedented, evolutionary conserved core enzyme (FAMIN) of energy metabolism that prevents inflammation and autoimmunity. Genetic loss of function causes monogenic Still's disease (a childhood fever syndrome with arthritis) and Crohn's disease (an inflammatory bowel disease), and a common hypomorphic variant predisposes for Crohn's disease and leprosy (a chronic infection). Cader et al, Cell 2020 Jan 23, DOI 10.1016/j.cell.2019.12.017 and Saveljeva et al, Cell Metab 2022 Jan 4, DOI 10.1016/j.cmet.2021.12.009

We search for an enthusiastic, talented cellular and molecular immunologist, who shares our passion for discovery and who is looking for an exciting challenge within our highly multidisciplinary group. Experience with in vivo experimentation and a personal license are essential for the role. Interest in metabolism and a broad skill set in molecular biology would be desirable.

Our lab is located in the new Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), for more info, see https://www.citiid.cam.ac.uk and http://www.med.cam.ac.uk/kaser/.

Fixed Term: Funding is available for this post for 1 year in the first instance.

Informal enquiries are welcomed and can be directed to Professor Arthur Kaser FMedSci (ak729@cam.ac.uk).

To apply online for this vacancy and to view further information about the role, please click 'Apply' above.

Applicants must have (or be close to obtaining) a PhD.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38, £34,610) moving to Research Associate (Grade 7, SP 41, £37,694) upon confirmation of your PhD award.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference RC49234 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.