Research Associate in Early Human Development (Fixed Term)

Applications are invited for a Research Associate position in Dr Maria Rostovskaya's group at the Gurdon Institute, University of Cambridge. This position is funded by a Medical Research Council Career Development Award to Dr Rostovskaya.

Our lab investigates the molecular and epigenetic mechanisms that regulate cell fate decisions during early human development. We are particularly interested in how these decisions occur at the right time and in the correct order. We combine human pluripotent stem cell-based models of early development with targeted genetic and epigenetic perturbations, genomics and single-cell molecular analyses, and computational modelling to uncover the principles guiding human embryogenesis.

For more information about the laboratory please visit https://www.gurdon.cam.ac.uk/people/maria-rostovskaya/

We are seeking a talented and highly motivated postdoctoral researcher to lead a project investigating the molecular and epigenetic control of lineage specification using human pluripotent stem cells, by editing epigenetic states of regulatory elements and other experimental approaches. You will apply advanced wet-lab methods, including stem cell-based models, chromatin biochemistry, CRISPR-based genetic and epigenetic editing tools, high throughput sequencing, as well as bioinformatic analysis.

The ideal job holders will have a strong interest in developmental mechanisms, including lineage specification and epigenetic gene regulation, and possess a combination of appropriate wet-lab and computational skills. Prior experience in stem cell and developmental biology is required, while experience in computational genomics would be an advantage. Recent first-author research publications or preprints (within the past two years) are highly desirable.

Candidates are expected to hold (or soon to be awarded) a PhD in stem cell biology, developmental biology, or a related discipline, and demonstrate excellent scholarly outputs. Applicants should provide evidence of a strong interest in developmental biology through relevant experiences and expertise and articulate their career vision in the cover letter. Applicants should have excellent communication skills and should be able to work both independently and as part of a team. The group offers a supportive and intellectually stimulating environment and mentorship for the candidate to develop their unique research identity.

Fixed-term: The funds for this post are available for 3 years in the first instance.

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Please quote reference PR49415 on your application and in any correspondence about this vacancy.

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