Job Title: Research Officer, Laboratory of Precision Disease Therapeutics (GIS)

Requisition ID: 1493

Posting Start Date: 22/04/2026

Description

The lab focuses on therapeutic target discovery and translational development for metabolic dysfunction-associated steatotic liver disease (MASLD), with a strong emphasis on siRNA-based therapeutics.

Our research integrates patient-derived multi-omics datasets with in vivo functional genetic screening and human in vitro disease models to systematically identify and validate clinically relevant therapeutic targets.

Requirements

• Bachelor's or Master's degree in Biomedical Sciences or related fields
• Prior experience in molecular biology and mammalian cell culture
• Experience with hepatocyte models, metabolic disease, or RNA-based techniques is advantageous
• Experience with animal work (mouse handling, injections, tissue collection) is a plus
• Strong organizational and problem-solving skills
• Ability to work independently and collaboratively in a fast-paced environment

Preferred Qualifications (Not Required but Advantageous)

• Experience in liver disease or metabolic disease research
• Experience with siRNA or gene knockdown approaches
• Familiarity with histology or imaging-based assays
• Experience working in translational or interdisciplinary research settings

Interested candidates are invited to send a cover letter stating your research interests and experience, curriculum vitae, and the names and email addresses of three references to LEE Yong-An (Lee_Yong-An@a-star.edu.sg)

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.