Collaborate with PI and researcher team to design and conduct biochemical assays for protein-small molecule interactions, binding affinity, target engagement, protein stability, aggregation, and related small-molecule characterization studies; assist with assay optimization.Perform molecular and cell biology experiments according to research plan, including cloning/construct preparation, mammalian cell culture, compound treatment, immunoblotting, immunostaining, and related cell-based assays.Perform fluorescence/confocal imaging and quantitative image/data analysis; organize, interpret, and present experimental results, prepare analysis for research reports, and maintain accurate research records.Maintain experimental workflows, reagents, constructs, cell lines, and laboratory equipment; assist with protocol development, troubleshooting, and preparation of figures/research reports.Knowledge, Skills and Abilities:- Knowledge of basic principles of protein biochemistry, molecular biology, cell biology, and quantitative experimental design.
- Skilled in recombinant protein expression/purification and protein characterization; experience with chromatography/FPLC, affinity purification, SDS-PAGE, or Western blotting.
- Skilled in mammalian cell culture, molecular cloning, immunostaining, fluorescence/confocal imaging, and quantitative data analysis.
- Ability to conduct components of research projects according to established plans, collect and analyze data, identify problems, and work collaboratively with senior researchers.
- Ability to learn and perform protein-small molecule binding and biophysical assays (e.g., SPR, BLI, MST, thermal-shift or related approaches) and to optimize assay conditions.
- Ability to troubleshoot identifiable experimental problems, maintain rigorous records, communicate results, and work both independently on assigned tasks and collaboratively within a research team.
This job posting reflects the general nature and level of work expected of the selected candidate(s). It is not intended to be an exhaustive list of all duties and responsibilities. The institution reserves the right to amend or update this description as organizational priorities and institutional needs evolve.Minimum Qualifications- Bachelor's degree in biochemistry, molecular biology, cell biology, chemistry, chemical biology, pharmaceutical sciences, neuroscience, or a related field, or equivalent advanced learning attained through experience.
- One year of relevant laboratory research experience may be required, consistent with the Research Professional I classification.
Preferred Qualifications - Prior hands-on experience in recombinant protein purification/characterization, protein biochemistry, molecular biology, cell culture, imaging, or small-molecule/drug-discovery assays.
- Experience with protein-small molecule binding assays or assay development/optimization is particularly valuable. The position will provide opportunities to contribute to research presentations and publications.
FLSA: Exempt
Full Time/Part Time: Full Time
Number of Hours Worked per Week: 40
Job FTE: 1.0
Work Calendar: Fiscal
Job Category: Research
Benefits Eligible: Yes - Full Benefits
Rate of Pay: $47,356 - $59,195
Compensation Type: salary at 1.0 full-time equivalency (FTE)
Grade6
Compensation GuidanceThe
Rate of Pay Field represents the University of Arizona's good faith and reasonable estimate of the range of possible compensation at the time of posting. The University considers several factors when extending an offer, including but not limited to, the role and associated responsibilities, a candidate's work experience, education/training, key skills, and internal equity.
The
Grade Range represent a full range of career compensation growth over time. The university offers compensation growth opportunities within its career architecture. To learn more about compensation, please review our
Applicant Compensation Guide and our
Total Rewards Calculator.
Career Stream and LevelPC1
Job FamilyResearchers & Scientists
Job FunctionResearch
Type of criminal background check required: Name-based criminal background check (non-security sensitive)
Number of Vacancies: 1
Contact Information for CandidatesXinglong Wang I
XWang@pharmacy.arizona.eduOpen Until Filled: Yes
Documents Needed to Apply: Resume and Cover Letter
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