CalTech - California Institute of Technology Jobs

CalTech - California Institute of Technology

Applications Close:

Pasadena

5 Star Employer Ranking

"Research Scientist"

Academic Connect
Applications Close
Is this job right for you? View Vital Job Information and Save Time

Research Scientist

Staff

2026-05-10

Location

Pasadena

Caltech

Type

Full-time Term, Exempt

Salary

$59,800 - $75,000 Per Year

Required Qualifications

PhD in biological sciences
5+ years postdoctoral experience
Molecular biology, mitochondrial & ER biology, autophagy knowledge
3+ years whole-genome CRISPRi screens
3+ years cell biology experiments (live tracking, IF, tissue culture, flow cytometry)
2+ years mass-spectrometry proteomics

Research Areas

Cellular stress regulation
Mitochondrial degradation
Endoplasmic reticulum degradation
Autophagy
Phosphorylation events
79% Job Post Completeness

Our Job Post Completeness indicates how much vital information has been provided for this job listing. Academic Jobs has done the heavy lifting for you and summarized all the important aspects of this job to save you time.

Research Scientist

Position Description

Research Scientist

Job Category
Fulltime Term

ExemptOvertimeEligible
Exempt

Benefits Eligible
Benefit Based

Apply Now

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.


Job Summary

The position is for a research scientist who will study the role of cellular stress in regulating the degradation of mitochondria and endoplasmic reticulum.

Essential Job Duties

  • Design and conduct experiments to investigate how cellular stress regulates endoplasmic reticulum degradation (35%)
  • Design and conduct experiments to investigate how cellular stress regulates mitochondrial degradation (20%)
  • Apply molecular biology techniques to resolve how phosphorylation events regulate endoplasmic reticulum degradation (15%)
  • Execute and analyze whole‑genome CRISPRi screens to find factors responsible for endoplasmic reticulum and mitochondrial degradation (15%)
  • Prepare research reports and presentations for internal meetings, publications, and conferences (15%)

Basic Qualifications

  • PhD in biological sciences
  • Five years postdoctoral experience
  • Detailed knowledge of molecular biology, mitochondrial biology, endoplasmic reticulum biology, and autophagy
  • At least 3 years of experience with whole-genome CRISPRi screen
  • At least 3 years of experience performing cell biological experiments independently, including live cell tracking, immunofluorescence, tissue culture, flow cytometry
  • At least 2 years of experience with mass-spectrometry-based proteomics

Preferred Qualifications

  • Experience mentoring undergraduates or graduate students
  • Experience presenting at international scientific meetings

Required Documents

  • Resume

Hiring Range

$59,800 - $75,000 Per Year

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off (vacation, holidays, sick time, parental leave, bereavement, etc.), tuition reimbursement, and more. Non-benefit eligible employees will have access to some benefits such as onsite counseling and sick time. Learn more about our benefits and staff perks.

Tell them AcademicJobs.com sent you!

Apply Now

Frequently Asked Questions

🎓What are the required qualifications for this Research Scientist role at Caltech?

Candidates must hold a PhD in biological sciences with five years of postdoctoral experience. Essential expertise includes detailed knowledge of molecular biology, mitochondrial biology, endoplasmic reticulum biology, and autophagy. Require at least 3 years with whole-genome CRISPRi screens, independent cell biological experiments (live cell tracking, immunofluorescence, tissue culture, flow cytometry), and 2 years of mass-spectrometry-based proteomics. Explore research jobs for similar roles.

🔬What does the Research Scientist do daily at Caltech?

Core duties: Design/conduct experiments on cellular stress regulating endoplasmic reticulum degradation (35%) and mitochondrial degradation (20%); apply molecular biology for phosphorylation studies (15%); execute/analyze whole-genome CRISPRi screens (15%); prepare reports/presentations (15%). Focus on independent research in Pasadena lab. See postdoc opportunities for related paths.

💰What is the salary and benefits for this Caltech Research Scientist position?

Hiring range: $59,800 - $75,000 per year, based on experience/equity. Benefits-eligible: health/dental/vision insurance, retirement, generous PTO (vacation, holidays, sick, parental), tuition reimbursement. Non-benefit staff get counseling/sick time. Details at Caltech benefits page. Check university salaries.

📝How do I apply for the Research Scientist job at Caltech Pasadena?

Submit resume via the official link: Apply Now. Deadline: May 10, 2026. Tailor your CV for CRISPRi and proteomics experience. Use our free resume template for academics.

What preferred qualifications enhance my candidacy for this role?

Preferred: Experience mentoring undergraduates/grad students and presenting at international scientific meetings. Strong fit for those with postdoc success in autophagy or organelle biology. Build skills via postdoc advice. Ideal for advancing to faculty; view faculty jobs.

🚀Is this Research Scientist position suitable for recent postdocs?

Requires five years postdoctoral experience, so best for mid-career researchers with proven independence in CRISPRi screens and cell biology. Recent postdocs may gain experience first via clinical research jobs or research assistant roles. Full-time term at Caltech offers stability in Pasadena.
3,634 Jobs Found

CalTech - California Institute of Technology

Pasadena
Staff / Administration
Add this Job Post to Favorites
Closes: May 10, 2026

MIT - Massachusetts Institute of Technology

Staff / Administration
Add this Job Post to Favorites
Closes: May 10, 2026

CalTech - California Institute of Technology

Pasadena
Staff / Administration
Add this Job Post to Favorites
Closes: May 10, 2026

CalTech - California Institute of Technology

Pasadena
Staff / Administration
Add this Job Post to Favorites
Closes: May 10, 2026
View More