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Posted Job Title
Research Specialist A
Job Profile Title
Research Specialist A
Job Description Summary
The Paralkar Lab (https://paralkarlab.med.upenn.edu/) in the Division of Hematology/Oncology at the University of Pennsylvania is seeking a motivated, full-time junior research technician. Our research focuses on the regulation of ribosome biogenesis in hematopoiesis (blood cell development) and leukemias using cutting-edge techniques and experimental systems. The technician will engage in projects utilizing cell-lines, primary human leukemia cells, and mouse models to investigate the mechanisms of ribosomal RNA transcription and nucleolar stress responses. This position provides an exceptional training environment where the technician will work with an experienced postdoctoral fellow while gaining hands-on exposure to advanced molecular biology assays (CRISPR, RNA-seq, and ChIP-seq) and sophisticated disease models (patient-derived xenografts). Part of the technician's duties will also include lab management operations, such as mouse husbandry, ordering supplies, and ensuring lab safety compliance. The ideal candidate is an academically outstanding college graduate who possesses a passion for basic science, strong organizational skills, and a desire to contribute meaningfully to biomedical discovery. Applicants must have at least some prior experience working in a molecular biology lab. Experience with computational biology, flow cytometry, or mouse handling is a plus.
Job Description
Job Responsibilities
- Cell culture and studies
- Mouse studies, husbandry, genotyping dissection, tissue analysis, flow cytometry
- Protein-based studies - western blotting, immunoprecipitation
- DNA/RNA based studies - CRISPR, RNA-seq, ChIP-seq, cloning
- Lab safety supervision, placing orders, equipment management
- Drive a research project (collect, analyze and interpret data, and present data at group meetings)
- Help in the general running of the lab, including: ordering, receiving items, and maintaining lab organization
- Other duties and responsibilities as assigned
Position contingent upon funding.
Qualifications
- Bachelor of Science and 0 to 1 year of experience or equivalent combination of education and experience is required.
Job Location - City, State
Philadelphia, Pennsylvania
Department / School
Perelman School of Medicine
Pay Range
$45,278.00 - $50,000.00 Annual Rate
Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job's level. Internal organization and peer data at Penn are also considered.
Equal Opportunity Statement
The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state or local law.
Special Requirements
Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
