Department: 194001 - Department of Molecular Biomedical Sciences

Location: Raleigh, NC

Essential Job Duties:
The Burclaff Lab is interested in better understanding how metabolism and cellular energetics are regulated within intestinal stem cells and how dynamic regulation underlies the intestine's ability to maintain itself at homeostasis and following injuries or disease. Our major focus is on the stem cell compartment, studying how the intestinal stem cells maintain their identity, undergo fate decisions, regulate cell cycle, and the dynamic plasticity that occurs within crypt populations following injury. We use a mix of animal and human models, including cutting-edge genetically modified primary human intestinal stem cell cultures, to advance our understanding of the mammalian intestine.

Position Overview

We are seeking a motivated, detail-oriented team member to support research operations, assisting with experiments, and assist with lab management. This role combines hands-on scientific research with core lab oversight in a collaborative environment.

Key Responsibilities & Qualifications

• Research & Lab Work: Execute experiments using animal models (mouse line maintenance/tissue collection), cell lines, and primary cultures. Perform molecular biology techniques (RNA/protein work, staining, tissue sectioning, live-image analysis).
• Lab Management: Oversee day-to-day operations, manage equipment and inventory, and coordinate multiple concurrent projects.
• Data & Documentation: Maintain accurate records, manage scientific data, and contribute to publications, grant applications, and presentations.
• Technical & Problem-Solving Skills: Prior research experience required. Proficient in standard lab equipment, troubleshooting, computers, and data management tools.
• Work Ethic & Soft Skills: Self-motivated, highly organized, and able to work independently while fostering a collaborative, supportive team environment.

Other Work/Responsibilities:
In addition to the core responsibilities of this role, there may be occasional opportunities to take on additional duties. This offers an opportunity to build on your skills, explore new areas, and gain a deeper understanding of the department's operations.

Minimum Experience/Education:
Demonstrated possession of the competencies necessary to perform the work.

Required Qualifications:
N/A

Preferred Qualifications:

• Experience working in a research lab
• Experience in mammalian primary cell culture (establishment and maintenance)
• Experience in molecular biology and biochemistry techniques (PCR; RT-qPCR; gel electrophoresis,
• DNA, RNA, and protein extraction; immunofluorescence; immunohistochemistry)
• Experience in mouse colony management (animal handling, breeding, weaning, genotyping, etc) and in vivo experimentation

Required license or certification:
N/A

Position Number: 00112275

AA/EEO Statement:
NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-513-0574 to speak with a representative of the Office of Equal Opportunity.

If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu.

Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.

NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.

Department: 194001 - Department of Molecular Biomedical Sciences

Location: Raleigh, NC

Essential Job Duties:
The Burclaff Lab is interested in better understanding how metabolism and cellular energetics are regulated within intestinal stem cells and how dynamic regulation underlies the intestine's ability to maintain itself at homeostasis and following injuries or disease. Our major focus is on the stem cell compartment, studying how the intestinal stem cells maintain their identity, undergo fate decisions, regulate cell cycle, and the dynamic plasticity that occurs within crypt populations following injury. We use a mix of animal and human models, including cutting-edge genetically modified primary human intestinal stem cell cultures, to advance our understanding of the mammalian intestine.

Position Overview

We are seeking a motivated, detail-oriented team member to support research operations, assisting with experiments, and assist with lab management. This role combines hands-on scientific research with core lab oversight in a collaborative environment.

Key Responsibilities & Qualifications

• Research & Lab Work: Execute experiments using animal models (mouse line maintenance/tissue collection), cell lines, and primary cultures. Perform molecular biology techniques (RNA/protein work, staining, tissue sectioning, live-image analysis).
• Lab Management: Oversee day-to-day operations, manage equipment and inventory, and coordinate multiple concurrent projects.
• Data & Documentation: Maintain accurate records, manage scientific data, and contribute to publications, grant applications, and presentations.
• Technical & Problem-Solving Skills: Prior research experience required. Proficient in standard lab equipment, troubleshooting, computers, and data management tools.
• Work Ethic & Soft Skills: Self-motivated, highly organized, and able to work independently while fostering a collaborative, supportive team environment.

Other Work/Responsibilities:
In addition to the core responsibilities of this role, there may be occasional opportunities to take on additional duties. This offers an opportunity to build on your skills, explore new areas, and gain a deeper understanding of the department's operations.

Minimum Experience/Education:
Demonstrated possession of the competencies necessary to perform the work.

Required Qualifications:
N/A

Preferred Qualifications:

• Experience working in a research lab
• Experience in mammalian primary cell culture (establishment and maintenance)
• Experience in molecular biology and biochemistry techniques (PCR; RT-qPCR; gel electrophoresis,
• DNA, RNA, and protein extraction; immunofluorescence; immunohistochemistry)
• Experience in mouse colony management (animal handling, breeding, weaning, genotyping, etc) and in vivo experimentation

Required license or certification:
N/A

Position Number: 00112275

AA/EEO Statement:
NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-513-0574 to speak with a representative of the Office of Equal Opportunity.

If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu.

Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.

NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.