CalTech - California Institute of Technology Jobs

CalTech - California Institute of Technology

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Pasadena

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"Research Technician"

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Research Technician

Staff

May 10, 2026

Location

Pasadena, CA

Caltech

Type

Full-time Term, Overtime Eligible

Salary

$25.25 - $30.75 Per Hour

Required Qualifications

Bachelor’s in Biology or related
2+ years lab experience
Mouse husbandry & handling
Behavioral assessments
RT-qPCR, ELISA, Western Blot
Data analysis (Excel, PRISM, R)

Research Areas

Microbiome mechanisms
Autism spectrum disorder
Rodent behavioral models
In vivo experiments
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Research Technician

Position Description

Research Technician

Job Category
Fulltime Term

ExemptOvertimeEligible
Overtime Eligible

Benefits Eligible
Benefit Based

Apply Now

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.


Job Summary

The Division of Biology and Biological Engineering at Caltech seeks a highly skilled and well-organized Research Technician to assist with research with the Mazmanian group. The Research Technician will perform in vivo experiments, including rodent handling, rodent breeding, tissue collection, and behavioral assessments. This role plays a key part in advancing our understanding of microbiome-related mechanisms in autism spectrum disorder.

Essential Job Duties

  • Perform a range of in vivo techniques, including mouse handling, behavioral assessments, and tissue collection.
  • Lead testing in animal models of emotional behavior.
  • Conduct various laboratory assays, including biochemistry/molecular biology assays.
  • Analyze and interpret experimental data, and prepare scientific documents including report findings, protocols, and other related materials for presentations, regulatory submissions, and publications.
  • Handle other related lab responsibilities as assigned.

Basic Qualifications

  • Bachelor’s degree in biology or related field.
  • 2+ years of relevant experience.
  • Wet laboratory experience in a biology or related discipline, including basic laboratory techniques (pipetting, centrifugation, solution preparation) and technical experience with RTqPCR, ELISA, western blotting, etc.
  • Previous experience with mouse models of behavior.
  • Experience in mouse husbandry and daily animal care, including cage maintenance, health monitoring, and proper handling.
  • Ability to collect and analyze data on mouse behavior and document findings using Excel, PRISM, R, etc.
  • Strong verbal and written communication skills for effective collaboration and documentation, including contributing to study reports.
  • Ability to work in a collaborative team environment and independently.
  • Ability to maintain detailed experimental records and protocols.
  • Able to maneuver and handle heavy wheeled equipment, remain on your feet for an entire shift, perform repetitive tasks, and lift, push, pull, or carry objects weighing up to 25 lbs.

Preferred Qualifications

  • B.S. in Biology, Neuroscience, Bioengineering, or a related discipline, with 2+ years of research experience.
  • Hands-on experience conducting in vivo research with mice.
  • Experience with behavioral assays such as Ultrasonic Vocalizations (USV), Elevated Plus Maze (EPM), and social interaction tests (including grooming), to assess anxiety, social communication, and repetitive behaviors in rodent models.
  • Strong organizational and analytical skills to manage multiple projects simultaneously.
  • Knowledge of and demonstrated adherence to regulatory requirements, including IACUC, IBC, IRB, and Environmental Health & Safety (EH&S) procedures.

Required Documents

  • Resume

Hiring Range

$25.25 - $30.75 Per Hour

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off (vacation, holidays, sick time, parental leave, bereavement, etc.), tuition reimbursement, and more. Non-benefit eligible employees will have access to some benefits such as onsite counseling and sick time. Learn more about our benefits and staff perks.

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Frequently Asked Questions

🎓What are the basic qualifications for this Research Technician role at Caltech?

Candidates need a Bachelor’s degree in biology or related field, plus 2+ years of relevant experience. Essential skills include wet laboratory techniques (pipetting, centrifugation, solution prep), RT-qPCR, ELISA, western blotting, mouse models of behavior, mouse husbandry, and data analysis with Excel, PRISM, R. Strong communication and teamwork are required. Explore research assistant jobs for similar roles or tips on thriving in research.

🧪What are the essential job duties for this position?

Duties include performing in vivo techniques like mouse handling, breeding, tissue collection, and behavioral assessments. Lead testing in animal models of emotional behavior, conduct biochemistry/molecular biology assays, analyze data, and prepare reports for publications. Other lab tasks as assigned. Check research jobs for more opportunities in rodent models.

What preferred qualifications will make me stand out?

Prefer B.S. in Biology, Neuroscience, or Bioengineering with hands-on in vivo mouse research. Experience with behavioral assays like Ultrasonic Vocalizations (USV), Elevated Plus Maze (EPM), social interaction tests. Strong organizational skills, multi-project management, and knowledge of IACUC, IBC, IRB, EH&S regulations. See research assistant excellence tips.

💰What is the salary and benefits for this Caltech Research Technician job?

Hiring range is $25.25 - $30.75 per hour, based on experience. Comprehensive benefits include health/dental/vision insurance, retirement plans, generous PTO (vacation, holidays, sick, parental), tuition reimbursement. Non-benefit staff get counseling and sick time. Learn more at Caltech's benefits page (external). Compare via university salaries.

📋How do I apply for this Research Technician position at Caltech?

Submit your resume via the official link: Apply Now. Deadline is May 10, 2026. Tailor your application to highlight mouse behavior experience and lab skills. Use our free resume template and cover letter template for academic jobs.

🐭Is experience with mouse behavioral models required?

Yes, previous experience with mouse models of behavior, including handling, husbandry, daily care, and data collection/analysis is required. Preferred: assays like USV, EPM, social/grooming tests for anxiety and repetitive behaviors in autism models. Physical ability to lift 25 lbs needed. View clinical research jobs for related in vivo roles.
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