Job Details

Johns Hopkins, founded in 1876, is America's first research university and home to nine world-class academic divisions working together as one university.

We are seeking a Research Technologist who will follow protocols and procedures to perform general laboratory duties and techniques. 50% of the time will be spent learning biochemical techniques, including cell culture, enzyme activity assays, RT-PCR, western blot, and immunohistochemistry. The remaining 50% of the time will be spent performing animal models of peripheral nerve crush and aging.

Specific Duties & Responsibilities

• Culture and maintain RAW macrophage cells and relevant macrophage, neuronal, Schwann cell, and muscle cell models for efficacy and mechanistic studies.
• Assist with evaluating glutamate carboxypeptidase II (GCPII) as a therapeutic target in peripheral nerve degeneration and the function of Schwann cells in aging.
• Study efficacy and pharmacokinetic properties of potential treatments using mouse models of peripheral nerve crush and aging.
• Maintain aged mouse colonies, including breeding, genotyping, and treating animals.
• Assist postdoctoral fellow in behavioral and electrophysiological assessments of aging mouse models.
• Assist in performing histological assessments of therapeutic efficacy in peripheral nerve crush and aging mouse models, including tissue collection, sectioning, and immunohistochemical staining. Perform miscellaneous related duties as assigned.

Minimum Qualifications

• Bachelor's Degree in Biology, Chemistry or related field.
• Additional education may substitute for required experience, and additional related experience may substitute for required education beyond a high school diploma/graduation equivalent, to the extent permitted by the JHU equivalency formula.