The project will investigate how the identity, density and arrangement of backbone-bound groups control DNA structure, molecular recognition and self-assembly. Functional groups - including hydrophobic, photoresponsive, catalytic or recognition motifs - will be introduced to create DNA-based micelles, droplets, fibres and other responsive nanostructures. The candidate will combine synthetic and bioconjugation chemistry with spectroscopy, microscopy, chromatography and DNA nanotechnology.
Our goal is to transform DNA from a biological molecule into a chemically programmable polymer, combining its sequence-level precision with the functional diversity of synthetic materials. The resulting systems could enable new approaches to biosensing, diagnostics, drug delivery, adaptive materials and synthetic biology.
Check out our group website here: rizzutogroup.org as well as related papers in JACS and Nature Chemistry.
Applying
Domestic or international students graduated or expecting to graduate with degrees in Chemistry, Biotechnology, Nanoscience or related disciplines are encouraged to apply. We are particularly looking for candidates with strong organic/supramolecular chemistry skills and/or experience in machine learning and AI methods.
If you meet the UNSW HDR admission requirements (including at least 9 months of research experience + a thesis or comparable written work), please send an email directly to Dr Felix Rizzuto (f.rizzuto@unsw.edu.au) with the following information:
Email subject: Prospective PhD for DNA nanotechnology
Please provide:
- Your background, experience, and research interests.
- When you expect to complete your current degree; and when you are be able to start your PhD if successful.
- A copy of your CV, along with undergraduate and any post-graduate academic transcripts.
- The names and contact information for 2 references.
Funding Notes
This is fully funded scholarship at the UNSW rate ($39,206 per annum for 3.5 years).
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