About the Job

Position Summary / Primary Purpose of Position: The Jain Lab (jain-lab.org) is seeking an experienced Research Professional 5 to serve as a key contributor to both the scientific mission and the operational needs of a growing biochemistry laboratory. The successful candidate will bring a strong foundation in protein biochemistry, cell biology, and genomic approaches, along with a demonstrated ability to keep a research environment organized and running effectively. Our lab investigates how histone post-translational modifications regulate transcription and associated processes, with relevance to both basic biology and disease.

This position is available immediately. The work schedule is Monday–Friday and is flexible.

Principal Position Functions:

60% Biochemical and Molecular Biology Research: Design, execute, and troubleshoot experiments investigating the regulatory roles of histone post-translational modifications and histone PTM-interacting proteins in transcription and associated processes, both in vivo and in vitro. Express, purify, and characterize recombinant proteins. Prepare plasmid DNA constructs, grow and harvest bacterial and mammalian cell cultures, and conduct biochemical and genomic analyses. Collect, analyze, and interpret experimental data. Maintain accurate and thorough research records.

25% Laboratory Operations: Manage day-to-day laboratory operations, including ordering and receiving supplies and reagents, maintaining and updating inventories and databases, and ensuring overall lab organization and cleanliness. Coordinate equipment maintenance and service. Train and mentor undergraduate students in laboratory techniques and safety protocols. Establish and maintain standard operating procedures (SOPs) for laboratory workflows.

10% Research Documentation: Work with the PI to plan and draft extramural research proposals and manuscripts reporting study results. Contribute to the preparation of presentations and other research communications.

5% Seminars and Other: Participate in lab group meetings, journal clubs, and relevant on-campus seminars and discussion groups. Other duties as assigned by the supervisor to support lab operations and research goals.

Work Schedule: Monday–Friday, flexible

Salary Range: $60,000–$70,000

Special Instructions: Application materials must include a resume/CV, a cover letter, and the contact information for 2–3 professional/academic references. The cover letter should describe previous research experience, relevant expertise in protein biochemistry and/or chromatin biology, any experience with laboratory operations, and how this position fits into your long-term career goals.