"Scientist I"

The Center for Immuno-Oncology (CIO) at the Dana-Farber Cancer Institute (DFCI) is seeking a research scientist to join the Tissue Biomarker Laboratory (TBL). The TBL provides pan-cancer clinical/translational correlative spatial biology studies and is an NIH-sponsored Cancer Immune Monitoring and Analysis Center. The laboratory is dedicated to the development and implementation of spatial analyses to study the tumor-immune microenvironment in biopsies from patients undergoing immunotherapy treatments. Multiplex immunofluorescence workflows include the Akoya Polaris and Lunaphore COMET platforms. The TBL research team works in conjunction with the CIO Computation Biology team on computational analyses to interpret these imaging datasets. The research is highly collaborative with a wide range of investigators across DFCI Disease Centers and other institutions to address their experimental questions. Many studies seek to identify biomarkers of response or resistance to immunotherapy using spatial biology analyses. Over the past 5 years, the laboratory has contributed to more than 50 publications (see https://ciopath.dfci.harvard.edu/ for more detail).

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

A qualified candidate should have a PhD in a biomedical-related discipline, such as immunology, biomedical engineering, and/or cancer biology, and experience in quantitative microscopy or computational data analysis. Responsibilities will include initiating and managing research projects, overseeing data collection and analysis, and working with the Principal Scientist and Faculty Director to prepare manuscripts and research proposals. Research projects will be collaborative studies involving extensive interactions with histopathology staff, research technicians, biomedical researchers, pathologists, clinicians, bioinformaticians, and data scientists. Experience working with teams and managing technicians is preferred.

License/Certification/Registration Required: None

Supervisory Responsibilities: No

Patient Contact: None

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.