Job Title: Senior Principal Scientist III, IMCB

Requisition ID: 2115

Posting Start Date: 11/05/2026

Job Description

Dr. Li Qi-Jing’s lab is seeking a Principal Scientist to lead the development of next-generation animal models for preclinical studies for drug discovery and development. The ideal candidate will bring deep expertise in in vivo disease modeling and support the development of innovative immune therapies.

Key Responsibilities

• Lead the design and development of novel cutting-edge animal models that could improve the predictive value of preclinical studies for drug development.
• Provide scientific leadership in study design, data interpretation, and decision-making for asset progression
• Collaborate closely with immunologists and other researchers to interpret data and refine experimental strategies.
• Mentor and guide junior scientists and contribute to building a strong translational research team
• Contribute to grant applications, publications, and strategic initiatives

Job Requirements

• PhD in Immunology, Molecular Biology, Genetics, or related fields.
• Extensive experience (typically 10+ years) in in vivo model development and translational research
• Strong scientific leadership with the ability to set strategy and drive execution
• Prior experience as an independent investigator (e.g., Associate/Professor or equivalent in industry) is strongly preferred
• Solid understanding of cancer biology and immunology, with a focus on immune cell therapies and tumor immunology

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.