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Senior Principal Scientist, IMCB
Job Description
The A*STAR Institute of Molecular and Cell Biology (IMCB) is inviting applications for a Senior Principal Investigator to lead a research programme in neuroscience, , with particular strengths in neurodegeneration, glial biology, cell fate reprogramming, and translational neuroscience. We seek an internationally recognised scientist with a strong track record in fundamental discovery and translational innovation to develop next-generation therapeutic strategies for neurological disorders. The successful candidate is expected to build a globally competitive programme that contributes to IMCB’s mission of advancing scientific discovery, enabling technology innovation, and supporting Singapore’s growing biotech ecosystem.
Key Responsibilities
- Develop and lead an internationally competitive and independent research programme in neuroscience, with a focus on neurodegeneration, glia-neuron interactions, neural cellular reprogramming, or related areas
- Drive innovative research in molecular and cellular neuroscience, including development of therapeutic strategies for neurological diseases
- Establish translational pipelines spanning target discovery, disease modelling, regenerative medicine, and preclinical validation
- Translate research discoveries into clinical, industrial, or commercial opportunities, including partnerships, and spinoff activities where appropriate
- Secure competitive external funding from national and international agencies
- Mentor and develop a high-performing research team
- Contribute to scientific leadership within IMCB and the broader Singapore biomedical research ecosystem
Qualifications and Requirements
- PhD, MD/PhD, or equivalent in Neuroscience, Molecular Biology, Biomedical Sciences, Regenerative Medicine, or a related discipline
- Strong publication track record in leading peer-reviewed journals such as Cell, Nature, Neuron, Cell Stem Cell or equivalent
- Proven ability to secure substantial competitive funding
- Track record of mentoring and developing successful trainees and junior scientists
- Excellent communication skills and a collaborative mindset
The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.
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