SLS-SF3. Uncovering a Drug-Sensitive Kinase Vulnerability in Parasitic Nematodes

About the Project

SLS-SF3. Uncovering a Drug-Sensitive Kinase Vulnerability in Parasitic Nematodes

Parasitic nematode infections such as lymphatic filariasis and river blindness affect millions worldwide, yet effective adult worm killing drugs are urgently needed. This PhD project will investigate vaccinia-related kinase (VRK) as a novel drug target using the model nematode C. elegans. The student will gain training in comparative genomics, AI-guided virtual screening, small-molecule screening, phenotypic imaging assays, RNAi and transcriptomics to understand how VRK controls parasite survival and development. This interdisciplinary project combines molecular biology and early-stage drug discovery, offering excellent opportunities for high-impact publications and collaborative research addressing global health challenges. For further information, please visit: https://ondb.org.uk/

Please contact Dr Alastair Barr to discuss: a.barr1@westminster.ac.uk

All doctoral researchers will have access to comprehensive personal and professional development training and a mentoring programme from the University of Westminster Graduate School. The researchers will join a School committed to decolonising and diversifying policies, practices and cultures within and beyond Higher Education.

Entry requirements and how to apply.

Candidates should have a minimum classification of 2.1 in their Bachelor's degree or equivalent, and preferably a Master’s degree. Applicants whose secondary level education has not been conducted in the medium of English should also demonstrate evidence of appropriate English language proficiency normally defined as IELTS: 6.5 (overall score with not less than 6.0 in any of the individual elements). You can read more about our entry requirements here: https://www.westminster.ac.uk/study/postgraduate/research-degrees/entry-requirements

How to apply: https://www.westminster.ac.uk/study/postgraduate/research-degrees/how-to-apply-for-a-research-degree

You can read more about what should be in a PhD research proposal here: https://www.westminster.ac.uk/study/postgraduate/research-degrees/entry-requirements/how-to-write-your-research-proposal

And about our Graduate School and the support they provide: https://www.westminster.ac.uk/research/graduate-school

To make an application, follow the link below to apply for the programme most appropriate to your research: https://www.westminster.ac.uk/study/postgraduate/research-degrees/research-areas/school-of-life-sciences

Applications should be submitted by 5pm on Friday, 15th May 2026. Interviews will take place in June.

You must include the code and title of the studentship you are applying for in your application header, i.e. “SLS-SF3 Studentship”.

For queries about any aspect of the application process or informal enquiries, contact our Doctoral Coordinator, Dr Polly Hayes: p.hayes@westminster.ac.uk