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Columbia University, New York, NY, USA

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"Technician B"

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Technician B

Position Summary

The department is seeking a motivated individual to assist/work on Stem Cell Regenerative Medicine to treat inherited dystrophies leading to blindness. diseases include retinitis pigmentosa, age-related macular degeneration, and Stargardt disease. The Technician B would be responsible for aiding the PI in performing administrative and writing-based tasks to support this research. They would also be responsible for helping laboratory members with manuscript editing and IRB/IACUC management, phenotype patients with known DNA mutations and testing the efficacy of stem cell transplantation and gene therapy.

Responsibilities

  • Patient specific stem cell disease modeling.
  • Carry out laboratory management duties including the ordering of laboratory equipment, reagents, chemicals, animals and general supplies.
  • Maintain equipment for histology, immunohistochemistry, light and fluorescent microscopy.
  • Manage mouse colonies and record keeping.
  • Under the supervision of the PI, assist with budgets and manage financial resources of the laboratory.
  • Administrative duties related to manuscripts/grant application.
  • Assist with preparing manuscripts/grant applications
  • Compose clinical research reports
  • Teach and train laboratory technicians and students.
  • Any other duties assigned

Minimum Qualifications

  • Bachelor’s degree in chemistry, biology or physics or related science or equivalent in education, training and experience
  • Excellent communication and writing skills
  • Must be able to work effectively with minimal supervision
  • Computer skills required

Preferred Qualifications

  • Previous experience working in a research laboratory setting desirable
  • Experience in grant application, project conducting, and manuscript preparation for paper submission
  • Broad knowledge and excellent skills in a wide-variety of molecular biology methods from very fundamental to advanced technologies, including tissue culture (cell line, primary cell, stem cell), mouse handling, mouse model creating (transgene, knock-in, knock-out), gene therapy/editing techniques (CRISPR, TALEN, Zinc finger) in vitro and in vivo, etc.
10

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