During the past two decades, blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) has become the scientific technique of choice for investigating human brain function in the field of cognitive neuroscience. It exploits the local alterations in blood flow produced by changes in neural activity, termed neurovascular coupling. However, BOLD fMRI does not measure neural activity directly and hence a fundamental problem exists: how to interpret BOLD signal changes and…
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