Research Assistant – Molecular and Cellular Biology - MLC 2690

About Us

The Mary Lyon Centre at MRC Harwell (MLC) is located in an expanding science and innovation park in Oxfordshire and is an internationally renowned centre at the forefront of genetics research. As the hub of the new National Mouse Genetics Network, the specialist facilities and capabilities of the MLC support a number of research groups across the UK to accelerate our understanding of human disease.

About You

You will need to have:

BSc in Biological Sciences or in a related subject
Understanding of genome engineering techniques (gene targeting, CRISPR-based tools)
Experience of working in a laboratory
Some initial experience in basic techniques of molecular biology e.g. PCR, cloning, or qPCR
Understanding of basic cell culture techniques (media preparation, sterile conditions)

Key Responsibilities

The culture of mouse embryonic fibroblast cells, immortalised cell lines, ES cells and organoid lines
Use of various electroporation techniques to develop novel ES cell lines with known genetic modifications and the quality control of those lines
Preparation of ES cells and organoid cell lines for micro-injection to generate mouse models
Extraction of mouse tissues
Sample management and communication of results internally

Other general duties required are to ensure the smooth running of a cellular biology laboratory, such as ordering reagents and other tasks that are shared with the rest of the team.

Benefits

Choosing to come to work at the MRC (part of UK Research and Innovation (UKRI)) means that you will have access to a whole host of benefits, from a defined-benefit pension scheme and excellent holiday entitlement, to access to employee shopping/travel discounts and a salary sacrifice cycle-to-work scheme. In addition, you will have the opportunity to contribute to the work of a world-class medical research organisation.

How to Apply

If you are ready to take on this exciting role and be part of a team dedicated to ground-breaking research, we would love to hear from you. For full details and to apply, please click on the 'Apply' button above. Please note: If you have been previously assessed against the above role criteria within the last 3 months, there is no need to reapply. Please quote reference MLC 2690. The closing date for applications is 31st August 2025.

Location:Didcot, HarwellSalary:£30,911 to £32,843 per annum, dependent on skills and experienceHours:Full TimeContract Type:PermanentPlaced On:14th August 2025Closes:31st August 2025Job Ref:MLC 2690 Mary Lyon Centre at MRC Harwell (MLC)

MRC - Mary Lyon Centre

"University Jobs at MRC - Mary Lyon Centre"

MRC - Mary Lyon Centre Employer Profile

Research Assistant – Molecular and Cellular Biology - MLC 2690