Māori and Pacific Perspectives on Strep A Vaccine Development: Insights from New PLOS Global Public Health Study in New Zealand

Understanding Group A Streptococcus and Its Devastating Impact in New Zealand

Group A Streptococcus (GAS), commonly known as Strep A, is a bacterium responsible for a range of infections from mild sore throats and skin infections to severe conditions like acute rheumatic fever (ARF), rheumatic heart disease (RHD), and invasive Group A Streptococcal disease (iGAS). In Aotearoa New Zealand, despite being a high-income country with universal healthcare, Strep A diseases impose a disproportionately heavy burden, particularly on Māori and Pacific populations. 92 91 Between 2000 and 2018, hospital admissions for ARF among children aged 5-14 years stood at 79.6 per 100,000 for Pacific children, 35.9 per 100,000 for Māori children, and just 1.6 per 100,000 for other ethnicities, highlighting stark inequities. 92 Recent data from 2023 shows Pacific peoples with iGAS rates of 37.5 per 100,000, Māori at 20.1, compared to 6.9 for European/Other and 5.6 for Asian populations. 9

These disparities stem from social determinants including overcrowding, poverty, poor housing, and systemic barriers rooted in colonization. Strep A infections often start asymptomatically or with minor symptoms, progressing to ARF—an autoimmune response damaging heart valves leading to lifelong RHD if untreated. In New Zealand, ARF rates among Pacific children are 80 times higher and Māori 36 times higher than other groups, perpetuating cycles of ill-health across generations. 92

The Burden of Strep A on Māori and Pacific Communities

Māori, the Indigenous Tangata Whenua of Aotearoa, and Pacific peoples, many of whom migrated post-World War II for labor, face entrenched health inequities. Overcrowded homes facilitate Strep A transmission via skin infections (pyoderma) and pharyngitis. A 2025 Auckland study captured the full spectrum of severe GAS disease, revealing high incidences in deprived areas: approximately 1 in 400 Pacific children under 10 and 1 in 200 Pacific adults over 80 affected annually. 4 iGAS notifications rose across all groups in 2023, with the sharpest increases among Pacific and Māori. 7

Personal stories underscore the toll: families recount young relatives needing heart surgery due to ARF complications. Economic costs are immense—GAS diseases cost New Zealand $29.2 million annually (2015 prices), with health burdens equivalent to 2,373 disability-adjusted life years. 0 Prevention efforts like sore throat swabbing have been resource-intensive but insufficient without addressing root causes.

A Groundbreaking PLOS Global Public Health Study Emerges

Published on February 4, 2026, in PLOS Global Public Health, the study "Māori and Pacific People's perspectives on Group A Streptococcus vaccine development and delivery in Aotearoa, New Zealand" provides critical insights into community views.Read the full study here 92 Led by Anneka Anderson from Te Kupenga Hauora Māori at the University of Auckland, the research team includes experts from the Departments of Molecular Medicine, Paediatrics, and Public Health at Auckland and Otago universities.

This qualitative study, part of the Rapua programme, interviewed 29 participants: 20 whānau members (13 Māori, 13 Pacific, 6 identifying with both) and 9 healthcare stakeholders between March and November 2023. Guided by Kaupapa Māori and Pacific-centred methodologies, it used semi-structured interviews analyzed thematically, validated by governance groups. 92

Perceptions of Acute Rheumatic Fever and Strep A Disease

Participants described ARF through lived experiences, linking it to colonization, poverty, and racism. Quotes like “I personally know a young man who had Strep throat and rheumatic fever and he’s 19 now and he’s due for heart surgery when he’s 21” illustrate generational impact. 92 Barriers include under-resourced primary care and lack of culturally safe services. Awareness is low, with calls for better sore throat management and advocacy.

Views on Strep A Vaccine Development

Overwhelming support for a vaccine as “prevention better than cure,” protecting vulnerable tamariki (children) and kaumātua (elders). However, concerns persist: masking social issues—“Creating a vaccine would just mask... overcrowding and other illnesses”—side effects, and mistrust from colonial history. 92 Demands include Māori/Pacific leadership, transparency, and integrating cultural knowledge like rongoā (traditional healing).

• Benefits: Protection for whānau, historical vaccine successes.
• Risks: Resource diversion from housing/poverty fixes.
• Process: Ethical, community-involved trials.

Preferred Models for Vaccine Delivery

Flexible, whānau ora (family wellbeing) approaches: home visits, mobile clinics, churches, marae, schools. “Through church... we have that open communication.” 92 Ethnically concordant providers, needle-free options, strengths-based info. COVID-19 lessons: Early community exclusion led to hesitancy; trusted leaders boosted uptake.

Cultural values underpin: hauora (holistic wellbeing), whanaungatanga (relationships), kotahitanga (unity), tino rangatiratanga (self-determination).Behind-the-paper insights

New Zealand Universities Driving Strep A Research

The University of Auckland leads via the Rapua programme, enhancing vaccine infrastructure and community engagement. Researchers like Nicole J. Moreland (Molecular Medicine) and Rachel Webb (Paediatrics) contribute to global efforts. 92 60 Recent Auckland studies map disease incidence, supporting vaccine candidates. Opportunities abound for academics in higher ed research jobs tackling health inequities.

Global Context: Strep A Vaccine Development Status

No licensed Strep A vaccine exists, despite WHO priority status. Challenges: Strain diversity (over 200 M-types). Candidates like StreptAnova (30-valent M-protein), VAX-A1, TeeVax1 in trials. 83 NZ's high burden positions it ideally for trials; 2025 human challenge trial in Melbourne advances efforts. 52 SAVAC consortium pushes for affordable vaccines.

Implications and Challenges for Equitable Vaccine Rollout

The study urges realigning healthcare to Māori/Pacific worldviews, strengthening workforces, and multipronged strategies. Vaccines as decolonization tools if community-led, upholding Te Tiriti o Waitangi. Risks: Perpetuating inequities without social fixes.

Photo by Michael Jerrard on Unsplash

Future Outlook and Calls to Action

Optimism for Strep A vaccines within years, informed by this research. NZ universities poised to lead; explore academic career advice or rate your professors. Policymakers must prioritize Indigenous voices. For researchers, check higher ed jobs in public health. Engaging whānau now builds trust for tomorrow's vaccines.

Internal links: NZ university jobs, research positions.