Rate My Professor Alex Leff

Leff's research interests encompass brain imaging studies of aphasia and alexia using fMRI and MEG to elucidate neural correlates of rehabilitation, alongside the design and testing of web-based therapies for cognitive, language, and visual impairments. Key projects include a longitudinal, randomized, double-blind trial combining cholinergic enhancement with behavioral therapy for Wernicke’s aphasia; the development and extension of Read-Right, a community-based web therapy improving text reading speed in hemianopic alexia (supported by The Stroke Association); and MEG investigations into behavioral rehabilitation for pure alexia. His major publications include “Spatial normalization of brain images with focal lesions using cost function masking” (NeuroImage, 2001), “Speech facilitation by left inferior frontal cortex stimulation” (Current Biology, 2011), “Biomarkers of stroke recovery: consensus-based core recommendations from the stroke recovery and rehabilitation roundtable” (International Journal of Stroke, 2017), and “Predicting language outcome and recovery after stroke: the PLORAS system” (Nature Reviews Neurology, 2010). These works have significantly influenced lesion-symptom mapping, prognostic modeling in stroke, and accessible neurorehabilitation strategies.