Rate My Professor Frederik Lermyte

Frederik Lermyte serves as a tenure track assistant professor in the Department of Chemistry, Faculty of Science, at the University of Antwerp. He completed his PhD in Chemical Sciences at the University of Antwerp in October 2016. His doctoral thesis, titled 'Development and application of novel methods for top-down and structural proteomics,' was supervised by Prof. Frank Sobott as promotor and Prof. Dirk Valkenborg as co-promotor. Prior to his doctoral studies, Lermyte studied Chemistry at the University of Antwerp. Following his PhD, he held an FNRS Research Fellowship at the University of Liège. His research specializes in the structure and interactions of biomolecules, particularly proteins essential to biological processes and disease contexts. Lermyte employs mass spectrometry techniques, focusing on the development and application of novel proteomics methods to analyze protein structures and other biopolymers, including oligonucleotides and carbohydrates. He leads projects such as the 'Development and application of novel proteomics methods,' spanning from 2012 to 2016, emphasizing MS-based analytical advancements.

Lermyte has made substantial contributions to biomolecular mass spectrometry, with 91 research works accumulating over 2,300 citations. Key publications include 'The simplest method yet for ultrafast desalting of proteins and oligonucleotides in native mass spectrometry' (Analytical Chemistry, 2026), 'Introducing a CATALYST to accelerate native affinity selection mass spectrometry' (Journal of the American Society for Mass Spectrometry, 2026), 'Native Taylor/non-Taylor dispersion-mass spectrometry (TNT-MS) allows rapid protein desalting and multiplexed, label-free ligand screening' (Small Methods, 2026), and highly cited works such as 'Top or middle? Up or down? Toward a standard lexicon for protein top-down and allied mass spectrometry approaches' (2019, 177 citations) and 'Higher-order structural characterisation of native proteins and complexes by top-down mass spectrometry' (2020, 161 citations). He edited the book 'Advanced Fragmentation Methods in Biomolecular Mass Spectrometry.' At the University of Antwerp, Lermyte teaches courses including 'Statistical treatment of empirical data' for Biochemistry and Biotechnology students, 'General chemistry' for Pharmaceutical Sciences, and 'Computer skills and statistical processing of measurements: part 1' for Chemistry undergraduates. He holds positions on the Department Council of Chemistry, Education Commission of Chemistry, and several study progress commissions.