Rate My Professor Mahmood Hussain

Mahmood Hussain, PhD, is Professor and Chair of the Department of Foundations of Medicine at NYU Grossman Long Island School of Medicine, part of NYU Langone Health. He also holds the position of Director and Endowed Chair of the Diabetes and Obesity Research Center. Previously, he served as Professor of Cell Biology and Pediatrics at SUNY Downstate Health Sciences University, where he was named Distinguished Professor in 2014. Hussain received PhD degrees from Oklahoma State University and the University of Copenhagen, Denmark, and holds a Licentiate of Medicine. His career has focused on advancing knowledge in lipid metabolism to address cardiovascular and metabolic diseases.

Hussain's research specializes in lipid and lipoprotein metabolism, particularly the molecular mechanisms of intestinal chylomicron assembly and secretion. He investigates the roles of apolipoprotein B, microsomal triglyceride transfer protein, miR-30c, circadian regulators like Bmal1, and other factors in lipid absorption, transport, and plasma lipid levels. His lab employs cell culture models, genetic mouse models, and biochemical approaches to identify therapeutic targets for lowering lipids in conditions such as obesity, diabetes, and atherosclerosis. With over 55 publications and more than 20,600 citations, key works include "Bmal1 regulates production of larger lipoproteins by modulating cAMP-responsive element-binding protein H and apolipoprotein AIV" (Hepatology, 2022), "Novel efficacious microRNA-30c analogs reduce apolipoprotein B secretion in human hepatoma and primary hepatocyte cells" (Journal of Biological Chemistry, 2022), "New Classification and Management of Abetalipoproteinemia and Related Disorders" (Gastroenterology, 2021), and "A simple, rapid, and sensitive fluorescence-based method to assess triacylglycerol hydrolase activity" (Journal of Lipid Research, 2021). Honors include the SUNY Chancellor's Award for Excellence in Scholarship and Creative Activities (2014), Irvine H. Page Award from the American Heart Association (1998), and the Dean's Honors Day Award for Distinguished Scientist.