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Pei-Yun Hon is an Assistant Professor in the Department of Medicine at the Yong Loo Lin School of Medicine, National University of Singapore (NUS). She serves as Principal Investigator leading research focused on antimicrobial resistance (AMR) transmission.
Her work includes a 2026 study that analyzed patient stool samples and hospital isolates, revealing how resistance genes transfer from harmless gut bacteria to dangerous hospital pathogens such as hypervirulent Klebsiella pneumoniae via plasmids. The research employed metagenomic sequencing to track gene flow and highlighted the role of the human gut as a reservoir for resistance mechanisms.
Explore NUS's critical role in combating antimicrobial resistance via innovative research, stewardship training, and policy influence amid rising antibiotics misuse in Singapore.
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