"Associate Computational Biologist"

Job Details

Posted: 01-Jan-26

Location: BOSTON, Massachusetts

Categories: Staff/Administrative

Internal Number: JR-277

The laboratory of Zuzana Tothova, MD, PhD is a multi-disciplinary team of physician scientists, scientists and computational biologists at the Dana-Farber Cancer Institute and the Broad Institute. Our laboratory uses genomics and a range of molecular and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders and to develop novel therapeutics. Our specific focus is to understand the role of chromatin modifiers and epigenetic factors and find novel therapeutic opportunities in myeloid malignancies, including myelodysplastic syndromes and acute myeloid leukemia.

JOB TITLE: Associate computational biologist
FLSA: Full-time, on-site
REPORTS TO: Zuzana Tothova, M.D., Ph.D.
DEPT: Medicine Oncology/ Heme Neoplasia

General Summary

A full-time associate computational biologist position is available in the laboratory of Zuzana Tothova, M.D., Ph.D. at Dana-Farber Cancer Institute.

We are seeking enthusiastic, self-motivated individuals who thrive in a fast-paced, challenging research environment, and can interact well with others as part of a cohesive team. If you have a desire to make a significant impact in healthcare and have the fortitude to work hard, you will succeed within this team.

This is an ideal entry-level or mid-level position into the world of cutting-edge laboratory research. A growth mindset and a willingness to take on challenging learning opportunities will be sought out traits. Ideal candidates will possess strong interpersonal skills along with a desire to help others to succeed.

Previous team members have gone on to successful academic and career opportunities; graduate/medical school and industry.

The candidate will be involved in a series of research activities, including computational analysis of large-scale data sets generated in in vitro and in vivo human disease relevant models and use of next generation sequencing with a special emphasis on understanding the biology of human myeloid malignancies.

The Associate Computational Biologist is training to become a Computational Biologist. They are responsible for routine data analysis or processing of biological data, with a focus on high-throughput technologies and genomic databases, under the supervision of mentor.

The Computational Biologist is a quantitative scientist who collaborates with scientific investigators and with other research staff in the analysis of high-throughput data, and dissemination of scientific results.

The Computational Biologist may work on many types of projects and areas of research including cancer genomics, functional genomics, immuno-oncology, molecular imaging, data management and integration, and querying biological databases.

We are looking for candidates with at least 2 years of availability.

• Data Processing Builds data processing pipelines to convert raw data into formats compatible with conventional statistical analysis and visualization under supervision of mentor
• Data Analysis: Follows a detailed manual to perform routine
• Data and Software Management: Monitors, downloads, organizes, and manages data from public data repositories or generated by collaborates
• Manuscript Preparation: Helps prepare tables and figures
• Research Portfolio Management: Trains to develops timelines and components for multiple routine projects; masters multi-tasking so that complex projects involving many interdisciplinary individuals move forward smoothly

KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:

• Knowledge of UNIX/Linux. Familiarity with scripting in Python and statistical programming using R
• Familiarity with principles of experimental design and the modern data analysis paradigms is required
• Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally with supervisory oversight
• Strong interpersonal skills - ability to effectively interact with all levels of staff and external contacts
• Excellent analytical, organizational and time management skills

MINIMUM JOB QUALIFICATIONS:

The position requires a bachelor's degree in a STEM field, with no prior experience necessary.

SUPERVISORY RESPONSIBILITIES: None

PATIENT CONTACT: None

Pay Transparency Statement: The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications. $60,000.00 - $67,466.00