Faculty Position (Open-Rank) in spatial omics of human diseases

Employer: Cleveland Clinic - Genomic Sciences and Systems Biology

Location: Cleveland, Ohio (US)

Salary: Competitive salary plus benefits

Closing date: Feb 19, 2026

Discipline: Life Sciences, Computational Biology, Genomics, Proteomics, Cancer Research, Epigenetics

Job Type: Faculty, Group Leader/Principal Investigator

Organization Type: Academia

Job Details

The Cleveland Clinic is searching for an Assistant, Associate or Full Professor-level faculty member to join its multidisciplinary Department of Genomic Sciences and Systems Biology on the Cleveland Clinic Research Institute. We seek a M.D., M.D./Ph.D., or Ph.D. scientist or physician-scientist with strong research expertise in spatial omics/multi-omics (i.e., experimental or computational genomics/epigenomics and proteomics) of human diseases who can lead an independent research group. A track record of independent NIH or equivalent funding (for Associate or Full Professor-level) and a high impact publication track record is required. The investigator will have the opportunity to train PhD/MD students at the Cleveland Clinic Lerner College of Medicine (CCLCM) at the Case Western Research Institute (CWRU) and is expected to collaborate with other faculty members across 25+ departments/center at Cleveland Clinic main campus and other locations. Candidates will expect to purse novel research ideas and develop cutting-edge spatial omics research technologies in applying to multiple human disease and health-related fields. Wet lab space is available for those whose work requires it. Strong computational infrastructures from the LRI high-performance computing (HPC) clusters, quantum computer (The IBM Quantum System One), and the Cleveland Clinic Data Center will be available. A generous start up package and support will be provided to the candidate.

Individuals will be appointed at Assistant, Associate, or Full Staff (equivalent to Assistant, Associate, or Full Professor, respectively) in the Department of Genomic Sciences and Systems Biology in Cleveland Clinic Research. For physician-scientists, joint appointments in clinical institutes will be made as appropriate. New recruits will join a highly collaborative environments within Cleveland Clinic LRI, with additional opportunities for collaboration and networking in the over 25 Departments and Centers at the Lerner Research Institute. Cleveland Clinic provides outstanding opportunities for interactions with basic, translational, and clinical investigators from multiple specialties. Researchers have access of richer clinical biospecimens from the Cleveland Clinic BioRepository (CC-BioR) and the Cleveland Clinic Pathology & Laboratory Medicine across multiple clinical institutes, such as Taussig Cancer Center, Heart, Vascular & Thoracic Institute (Miller Family), Neurological Institute, Respiratory Institute, and many other clinical departments. We have world-class core facilities (including Imaging Core, Genomics Core and Genome Center) with the opportunity to grow them through the substantial expansion of the Lerner Research Institute and the formation of the Global Center for Pathogen Research and Human Health.

Cleveland Clinic Research is an integrated research community consisting of 12+ Research Departments including genomic medicine, cardiovascular sciences, biomedical engineering, cancer biology, cell biology, immunology and inflammation, and neurosciences, and 10+ Centers of Research including cardiovascular research, anesthesiology research, cerebrovascular research, hematology and oncology molecular therapeutics, ophthalmic research, Alzheimer’s disease research, orthopedic research, structural biology, surgery research, thrombosis and vascular biology, and drug discovery and development (an annual budget of >$400 million). The mission of LRI is to understand the causes of human diseases and to develop new treatments and cures. The hallmark of LRI is its focus on disease-oriented research. This Institute fosters collaboration and interaction between clinicians, physician-scientists, and basic science researchers. More than 1,800 people (including approximately 200 principal investigators, over 250 postdoctoral fellows, and 100+ graduate students) work in ~200 labs conducting research projects focusing on cardiovascular, cancer, neurological, musculoskeletal, allergic and immunologic, eye, metabolic, and infectious disease.

Faculty typically also become members of the Molecular Medicine Graduate Training Program at our CCLCM and other programs at the neighboring Case Western Reserve University School of Medicine, providing access to excellent PhD/MD students and postdoctoral fellows. Cleveland Clinic Research provides comprehensive career development and mentorship for junior faculty via our formalized coaching faculty and programs. Candidates should submit a cover letter, curriculum vitae, and statement of research interests by email to Amy Petriella (petriea@ccf.org) and Gili Ornan (ornang@ccf.org)

Lab Research Topics:

• Spatial omic of human diseases
• Examples of Lab Research Topics include but are not limited to – single or multi-omics with or without imaging, single cell omics.
• Faculty members are expected to have a research focus on omics of complex diseases and translational biology research.

Education:

• PhD or MD/PhD required
• MD with relevant laboratory experience may substitute for PhD

Required Application Materials:

• Cover Letter
• CV
• Statement of research interests

All application materials should be submitted directly via email to the department at chengf@ccf.org, petriea@ccf.org, and ornang@ccf.org.

Contact:

Amy Petriella

petriea@ccf.org

Annual Salary Range for this Position: $130,000.00 - 350,000.00 USD

The pay range displayed on this job posting reflects the anticipated range for new hires. A successful candidate’s actual compensation will be determined after taking various factors into consideration such as the candidate’s work history, experience, skill set, and board certification. This is not inclusive of the value of Cleveland Clinic’s benefits package, which includes among other benefits, healthcare/dental/vision, and retirement.