"Clinical Research Nurse C/D (Abramson Cancer Center)"

Clinical Research Nurse C/D (Abramson Cancer Center)

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Posted Job Title

Clinical Research Nurse C/D (Abramson Cancer Center)

Job Profile Title

Clinical Research Nurse C

Job Description Summary

The Abramson Cancer Center at Pennsylvania Hospital's Clinical Research Unit seeks a full-time, Clinical Research Nurse (CRN) to conduct studies involving a wide variety of investigational products and various sponsors. This position will report directly to the Research Manager and work directly with Physician Investigators ("PI") on clinical research performed. This area of research requires dedicated attention and care to ensure subject safety and well-being. The successful candidate will comply with all policies relating to UPHS, JCAHO, GCP and other regulatory standards.

Job Description

Job Responsibilities

Clinical Research Nurse C Responsibilities

• Work in collaboration with Research Team Leaders and Principal Investigators with initiating study procedures for new IITs and industry-sponsored clinical trials. Manage all aspects of Phase I - IV clinical trials. Participate in the conduct of audits by study sponsors, CROs, the FDA, the Eastern Oncology Group, the University of Pennsylvania's CTSRMC, and other groups.
• Work directly with physicians to design, set-up and execute clinical trials. May be required to speak at investigator meetings or site initiation visits for investigator-initiated trials ("IITs") where physician is the national PI. Assist in analyzing data to determine response and clinical outcomes; assist with literature reviews; contribute to preparation of study abstracts, posters, manuscripts and grant applications.
• Develop and maintain ongoing communication with the clinical teams including, but not limited to laboratory, infusion, radiology, Advanced Practitioners, triage, inpatient and pharmacy. Provide in-service and support to infusion, infusion pharmacy, inpatient staff as appropriate. Provide ongoing service education updates to all investigators and PAH/HUP staff that have eligible participants for clinical research trials
• Care for subjects in all age groups from young adult through geriatrics. Coordinate activities of oncology team in caring for subjects. Administer or provide oversight of administration of medications, chemotherapeutic drugs, biologic response modifiers, cellular immunotherapies and other treatment agents or study interventions, as appropriate.
• Review all clinical and laboratory data and adverse events, reporting in real-time to the Principal Investigator (PI) for assessment and review, and communicate with medical staff regarding protocol-specific management of toxicities and adverse events.
• Triage any questions subjects may have regarding protocol specifics, investigational products, lab results, effects of therapies, medications, and symptom management within clinical scope and level of expertise and referring other questions to the PI or medical team in order to obtain guidance or assistance.
• If needed, collect, review and report timely, valid, accurate study data within the timelines specified by the Clinical Trials Agreement. Coordination may also include: transporting specimens, submission of study documents to all applicable institutional committees (e.g., IRB, CTSRMC, IBC, CHPS) for initial approval, continuing reviews and for approval of any amendments.
• Provide coverage and support to other research nurses and coordinators to meet departmental/organizational staffing needs.
• This position will require the research nurse to have a variable schedule. Research subjects are seen in the clinical setting during early morning and early evening hours as well as daytime visits. Position involves work-related responsibilities that may occur outside of usual hours and some conference-related travel.

QUALIFICATIONS:

• Registered Nurse with licensure in the Commonwealth of Pennsylvania without restriction or limitation. Bachelor's degree with 2 to 3 years of relevant experience or equivalent combination of education and experience required. Oncology experience highly preferred. Clinical research experience preferred but not required. BSN degree preferred.

Clinical Research Nurse D Responsibilities

The Clinical Research Nurse D will have the same duties as C but will include the following:

• This individual will work independently with minimal supervision. May act in a lead capacity or as back-up to supervisor.
• Work directly with physicians to design, set-up and execute studies. May be responsible for writing investigator initiated IND/IDE clinical trials in collaboration with faculty supervisor. Speak at investigator meetings or site initiation visits for IITs where collaborating physician is the Principal Investigator. Assist in analyzing clinical data to determine response and clinical outcomes; contribute to the preparation of study abstracts, posters, manuscripts and grant applications.
• Independently manage complex (i.e. multi-drug regimens, high toxicity potential, multiple random assignments, or immunotherapies, etc.) clinical trials and registries within the Pennsylvania Hospital Research Team.
• Provide coverage and support to other research nurses and coordinators to meet departmental/organizational staffing needs. Responsible for functional supervision of non-licensed personnel assigned to work with the nurse. Act in lead capacity in coordination of unit projects and assist unit managers in overseeing execution of project timelines as well as completion of study related activities delegated to research coordinator who provides study related support (e.g., regulatory submissions and data entry). Participate in core study team, disease-site group and ongoing protocol training/compliance meetings. Participate in working groups within the disease-site team that will maximize the efficiency and quality of research performed, including developing SOPs. Act as a mentor to newly hired staff.
• Represents the Pennsylvania Hospital Clinical Research Unit when meeting with Medical Science Liaisons, current and future research collaborators, and prospective donors; assists physician and unit manager in coordinating development plans. Participation in national meetings, as well as University department meetings and committees. Act as a facilitator and speak at community events organized by physicians in collaboration with non‐profit organizations.

QUALIFICATIONS:

• Registered Nurse with licensure in the Commonwealth of Pennsylvania without restriction or limitation. Bachelor's degree and 4 to 5 years of experience or equivalent combination of education and experience required, including 3-5 years of clinical research experience preferred. Oncology experience highly preferred. Master's degree in a science-related field preferred.

Position continuous upon funding.

Job Location - City, State
Philadelphia, Pennsylvania

Department / School
Perelman School of Medicine

Pay Range
$62,000.00 - $102,500.00 Annual Rate
Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job's level. Internal organization and peer data at Penn are also considered.

Equal Opportunity Statement
The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state or local law.

Special Requirements
Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

To apply, visit https://wd1.myworkdaysite.com/en-US/recruiting/upenn/careers-at-penn/job/Perelman-Center-for-Adv-Medicine/Clinical-Research-Nurse-D_JR00110224-1