"CRUK Research Fellow"

Applications are invited for a CRUK Research Fellow position to join the Cancer B-cell Group.

The successful candidate will have a PhD degree or equivalent EU qualification and experience. Knowledge and laboratory experience on tumour and/or normal B cell biology, and/or antibody generation/manipulation and development are highly desirable.

You will be an enthusiastic and well-motivated scientist, capable of developing your research project as well as a good team-player with excellent communication skills. You will test recently developed antibodies and generate new antibodies targeting specific structures of the tumour B-cell receptor (specifically those of chronic lymphocytic leukaemia and/or follicular lymphoma). These antibodies will be used for either diagnostic and therapeutic purposes; therefore, knowledge of the mechanisms of disease mediated by the interaction of the tumour B-cell receptor and environment can be part of the role, including performing in vitro and, where necessary, in vivo (animal models) studies in preparation of potential first-human studies. For this purpose, there will be a tight interaction between the Cancer B-cell group and Prof. Mark Cragg at the Antibody Vaccine Group, as part of national and international funded ongoing awards.

You will also interact with international academic collaborators, including those from Spain, Italy and USA, and with Industry. Contribution to the academic development and enhancement of the quality of research (e.g. preparation of new grant applications) and enterprise of the Cancer B-cell Group within the School of Cancer Sciences, nationally and internationally, and some supervision of junior staff and students are expected.

This post will be based within the School of Cancer Sciences, including the Centre for Cancer Immunology at the University Hospital Southampton campus, occupying modern, well-equipped, purpose-built laboratories, with support from clinical and laboratory-based colleagues.

Additional details about the School of Cancer Sciences can be found at: https://www.southampton.ac.uk/medicine/academic_units/academic_units/cancer_sciences.page

The position is funded by Cancer Research UK and is full-time, fixed-term till 31st August 2027, renewable if successful in future project applications.

For an informal discussion or to arrange a visit, please contact Prof Francesco Forconi f.forconi@soton.ac.uk and/or Prof Mark Cragg msc@soton.ac.uk

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.