Offer Description
Jagiellonian University (Poland) invites applications for the position of an Engineering and Technical Employee funded through the research project of the European Research Council (ERC) titled “In with the good, out with the bad: understanding small molecule influx and efflux in gut” (IN and OUT).
The human gut microbiome has a profound influence on many aspects of human health. The Bacteroides genus belongs to the Gram-negative Bacteroidetes phylum and is the most abundant genus in the guts of western world populations. Bacteroides have received much attention due to their ability to utilise dietary glycans that are inaccessible to the host ("fibre"). However, the ability to degrade fibre is unlikely to explain the dominance of Bacteroides, given the fibre-poor diets in western societies. Since microbial and epithelial cell turnover in the human gut is very high, there are many diet-independent nutrient sources within the gut, and we hypothesise that Bacteroides have evolved to efficiently utilise those. In addition, noxious compounds such as bile acids and antibiotics need to be removed from the cell. All these processes depend critically on lipoproteins, channels and transporters residing in the bacterial outer membrane (OM).
The EU-funded project "IN and OUT" aims to identify novel OM influx and efflux processes in gut Bacteroides via a multi-disciplinary approach to understand why this genus is so abundant. Compared to Proteobacteria like E. coli in which these processes have been studied in detail, OM influx and efflux in the phylogenetically distant Bacteroides is largely terra incognita. The first strand within the project (INFLUX) focuses on acquisition of abundant nutrients within the gut, such as proteins, peptidoglycan, nucleic acids and lipids. The second strand (EFFLUX) is dedicated to studying efflux pumps, which play important roles in removing toxic molecules like antibiotics and human drugs from the cell. In both projects you will discover novel biology that will contribute to our understanding why the genus Bacteroides is so abundant in the human gut.
Candidate’s profile:
You are curious about the natural world, in particular the "invisible" world of the micro-organisms that live on and in our bodies (the "microbiome"), and you are excited about the possibility to contribute to our understanding of this hidden world. This is a "wet lab" project, so you will spend a lot of time at the bench learning and doing experiments. Most of all, you'll be highly motivated and persistent with a strong work ethic: after all, experiments sometimes fail, but failure breeds success!
Where to apply
E-mail: job.mcb@uj.edu.pl
Requirements
Research Field: Biological sciences » Biology
Education Level: Master Degree or equivalent
Skills/Qualifications
- Academic interests aligned with the project’s scope, in particular in the areas of protein structure and function, bacteriology and the human gut microbiome.
- Very good command of English in speech and writing (minimum B2 level), sufficient to work with academic literature and communicate with international partners.
- Experience in academic or project work (e.g., participation in grants, publications, research collaboration), documented by achievements or certificates.
- Ability to organize one’s own work and work as part of a team; independence and punctuality in carrying out assigned tasks.
- Familiarity with issues related to the implementation of research projects funded by external sources (e.g., NCN, ERC, Horizon Europe) ‒ welcome asset.
- Knowledge of basic tools for data and project documentation management (e.g., MS Office, university systems).
Languages: ENGLISH
Level: Good
Additional Information
Benefits
- basic remuneration in the amount of 4 900 PLN gross;
- seniority allowance depending on length of service (3‒20%);
- regulation allowance in the range of 0‒30% of the basic remuneration, after meeting the conditions specified in the Regulation for remuneration of employees of the Jagiellonian University;
- jubilee awards for long-term service ‒ in accordance with the Regulation for remuneration of employees of the Jagiellonian University;
- possible task-based and periodic allowances, as well as discretionary awards, upon meeting the conditions set out in the Regulation for remuneration of employees of the Jagiellonian University;
- additional annual remuneration, the so-called "thirteenth salary" ‒ after meeting the conditions specified in the relevant regulation.
Benefits ‒ Institutional Social Benefits Fund (depending on the income per family member, in accordance with the Regulations for Granting Benefits from the Company Social Benefits Fund of the Jagiellonian University):
- co-financing of summer holidays (PLN 1 050–1 550 gross) and winter holidays (PLN 700–900 gross);
- co-financing for children for organised holidays (PLN 900–1 400 gross), or co-financing of individually purchased summer camps, sports camps, winter camps, medical holidays or rehabilitation stays (50–90%, with the maximum amount eligible for co-financing being PLN 2 500 gross) per child;
- cash equivalent for a special occasional package of sweets in the amount of PLN 100–300 gross per child;
- co-financing of childcare in nurseries, kindergartens and other forms of preschool education, as well as care provided by a daily guardian or nanny (PLN 250–400 gross).
We offer
- stable employment based on an employment contract at the renowned university,
- possibility of qualifications improvement and professional development,
- benefits in the form of i.a. Multisport card, sports activities, medical packages, group insurance,
- additional social benefits.
Eligibility criteria
- Completed master’s degree in microbiology, biochemistry or related fields.
- Doctoral student status no later than on the date of signing the agreement – in accordance with the project guidelines.
Additional comments
Required application documents
- resume,
- personal questionnaire filled in by the Candidate (F/M),
- copy of a diploma certifying graduation, or—if not available at the time of application—a confirmation from the dean’s office certifying the completion of final examinations and graduation.
Personal questionnaire template (no. 2) can be obtained at: https://cso.uj.edu.pl/en_GB/dokumkandyd
Form of submission
by e-mail to the address: job.mcb@uj.edu.pl
title: “Technician 958.1101.18.2026”
Website for additional job details: https://praca.bip.uj.edu.pl/stanowiska-nienaukowe/-/journal_content/56_INSTANCE_aKqG3d0TunKY/145868730/161420132
Work Location(s)
Number of offers available: 2
Company/Institute: Malopolska Center of Biotechnology
Country: Poland
State/Province: małopolska
City: Kraków
Postal Code: 30-387
Street: Gronostajowa
Contact
State/Province: małopolska
City: Krakow
Website: http://www.uj.edu.pl
Street: Golebia 24
Postal Code: 31-007
E-Mail: job.mcb@uj.edu.pl
Phone: 12 664 5369
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