Job Information
- Organisation/Company: Mikrogen
- Research Field: Biological sciences » Other
- Researcher Profile: Established Researcher (R3)
- Positions: Other Positions
- Application Deadline: 10 Oct 2026 - 14:43 (Africa/Abidjan)
- Country: Türkiye
- Type of Contract: Permanent
- Job Status: Full-time
- Is the job funded through the EU Research Framework Programme? Not funded by a EU programme
Offer Description
Functional Genomics & Functional Validation Researcher
Mikrogen Genetic Diagnosis Center is seeking a PhD-level researcher to join the research team of its planned Translational Genomics and Advanced Therapeutic Technologies Leading R&D Laboratory under the TÜBİTAK 1515 Programme.
The researcher will focus on the functional characterization of genetic variants, disease mechanisms and candidate molecular targets, linking genomic findings with experimental evidence through cell-based and molecular assays.
Main Responsibilities
- Designing and performing functional studies for candidate genetic variants
- Investigating the molecular and cellular consequences of disease-associated variants
- Developing and applying cell-based functional assays
- Establishing experimental models for rare and genetic diseases
- Performing gene expression, protein expression and pathway-level analyses
- Contributing to the functional interpretation and reclassification of variants, including VUS
- Working with patient-derived cells and, where appropriate, engineered cellular models
- Supporting studies aimed at identifying disease mechanisms and potential therapeutic targets
- Designing experimental validation strategies in collaboration with clinical genomics and bioinformatics teams
- Contributing to national and international R&D projects, scientific publications and patentable research output
Where to apply
E-mail: dilaratunca@triplehelix.life
Requirements
Research Field: Biological sciences
Education Level: Master Degree or equivalent
Skills/Qualifications
Required Qualifications
- PhD in Molecular Biology and Genetics, Cell Biology, Medical Biology, Genetics, Biotechnology, Biomedical Sciences or a closely related field
- Strong hands-on experience in functional genomics, molecular biology or cellular functional assays
- Experience in experimental investigation of genetic variants or disease mechanisms
- Advanced experience with techniques such as qPCR, RT-PCR, Western blotting, immunofluorescence, flow cytometry and cell culture
- Experience in mammalian cell culture and experimental model development
- Ability to independently design experiments, interpret results and troubleshoot experimental workflows
- Strong understanding of gene function, molecular pathways and genotype–phenotype relationships
- Scientific publication experience
Specific Requirements
Preferred Qualifications
- Experience in rare disease functional studies
- Experience with patient-derived cells, primary cells, iPSC or disease models
- Experience in CRISPR/Cas or other genome-editing approaches
- Experience with RNA studies, splicing assays or transcript-level functional analyses
- Experience in functional assessment of variants of uncertain significance (VUS)
- Familiarity with NGS-derived genomic findings and clinical variant interpretation
- Experience in gene/RNA-based therapeutic research
- Participation in national or international funded R&D projects
- Experience working in multidisciplinary teams combining genetics, bioinformatics and cellular biology
Languages: ENGLISH
Level: Excellent
Research Field: Biological sciences » Other
Years of Research Experience: 4 - 10
Additional Information
Work Location(s)
Number of offers available: 1
Company/Institute: 8591220342
Country: Türkiye
Contact
State/Province: Ankara
City: Ankara
Website: https://www.mikrogenlab.com
Street: Reşit Galip Caddesi No:18
Postal Code: 06680
E-Mail: dilaratunca@triplehelix.life
Phone: 05393978330
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