In Vivo Study Supervisor

MRC - Mary Lyon Centre

About the role

We have an exciting opportunity at the Mary Lyon Centre (MLC) to join our In Vivo team as a Study Supervisor. You will oversee the delivery of in vivo studies for external academic and biotech partners, using mouse models of human disease including cancer, mitochondrial and kidney disorders. Studies typically involve phenotyping, dosing, welfare assessment and tissue collection.

This role requires strong organisational skills to plan studies across teams, manage workflows and ensure high-quality, timely delivery. You will play a key role in quality control, assessing and managing day-to-day changes to study plans.  You will line manage two technicians and work closely with project managers and technical teams to successfully deliver studies.

About Us

The Mary Lyon Centre at MRC Harwell is located in an expanding science and innovation campus in Oxfordshire and is an internationally renowned centre at the forefront of genetics research.  As the hub of the new National Mouse Genetics Network, the specialist facilities and capabilities of the MLC support several research groups across the UK to accelerate our understanding of human diseases, such as cancer, developmental disorders and neurodegeneration.

Main Duties/Key Responsibilities will include:

• Day-to-day responsibility for running allocated studies. This involves being on the ground in the animal house, scheduling mouse cohorts, arranging technicians to cover tests, calculating doses and diluting drugs, organising appropriate training, ensuring that full plans are in place and that relevant paperwork (e.g. risk assessments and SOPs) is signed off by technicians.
• Develop SOPs and ensure these are read and adhered to.
• Troubleshoot problems that arise in studies, using your experience to make appropriate judgment on the best course of action.
• Generate study records and ensure that they are up to date and accurate.
• Ensure that all studies are compliant with Home Office regulations and undergo training to achieve a Home Office Licence to allow work on mice if required.
• Carry out basic plotting to check data such as mouse body weights vs treatment.
• Carry out quality control of data relevant to your studies, helping the data management and project management teams to ensure that all data is complete and correct.

About you

You will need to have:

• A Bachelor’s degree, with biological experience in an academic or commercial research setting or equivalent experience.
• Research experience, including working in a laboratory environment and with laboratory animals.
• Excellent attention to detail with experience in accurate record keeping for multiple studies.
• Flexible and adaptable in approach to work to ensure changing priorities and deadlines are met.
• Study management experience

Benefits

Choosing to come to work at the MRC (part of UK Research and Innovation (UKRI)) means that you will have access to a whole host of benefits, from a defined-benefit pension scheme and excellent holiday entitlement, to access to employee shopping/travel discounts and a salary sacrifice cycle-to-work scheme.  In addition, you will have the opportunity to contribute to the work of a world-class medical research organisation.

How to Apply

If you’d like to join us and be part of a team dedicated to ground-breaking research, we would love to hear from you. For full details and to apply, please click on the ‘Apply’ button above