"Levine Lab - Electrophysiologist (Assistant Professional Researcher)"

Levine Lab - Electrophysiologist (Assistant Professional Researcher)

Posted: 01-Jan-26

Location: San Francisco, California

Type: Full-time

Categories: Academic/Faculty

Internal Number: JPF05913

Department of Oral and Maxillofacial Surgery
University of California, San Francisco

The Levine Lab is seeking a skilled and motivated Electrophysiologist. Applications are being accepted for the position of Assistant Professional Researcher.

Key responsibilities:

• Ion Channel Biophysics: Conduct electrophysiological experiments using patch-clamp techniques to investigate ion channel properties and gating mechanisms in sensory neurons.
• Calcium Imaging: Use calcium imaging techniques (e.g., Fura-2, Fluo-4, GCaMP) to study intracellular calcium dynamics nociceptors.
• Neurophysiology: Investigate the role of ion channels in pain sensation and neural signaling by examining neuronal responses to pharmacological agents and mechanical, thermal, and chemical nociceptive stimuli.
• Human Sensory Neurons: Utilize primary human sensory neurons to study specific ion channel function.
• Data Analysis: Analyze large datasets from electrophysiology, imaging, and molecular experiments using appropriate software (e.g., MATLAB, Clampfit, ImageJ).
• Collaboration: Work alongside cross-disciplinary teams, including pharmacologists, molecular biologists, and computational biologists, to achieve research objectives.
• Documentation & Reporting: Prepare research reports, manuscripts for publication, and contribute to grant writing and lab compliance (e.g., IACUC, biohazard, BUA).

Required Qualifications:

• Doctorate in Physiology, Neuroscience, Biophysics, or a related field, plus 3+ years of relevant experience.
• Proficient in electrophysiology techniques (e.g., patch-clamp) and calcium imaging (e.g., Fura-2, GCaMP).
• Strong understanding of ion channel function and neuronal signaling pathways, especially in nociceptors.
• Data Analysis: Familiarity with tools such as MATLAB, Python, Clampfit, and ImageJ.
• Excellent written and verbal communication skills for preparing research reports and publications and institutional compliance.

Preferred qualifications:

• Advanced expertise in ion channel biophysics and electrophysiology.
• Experience working with rodent model and human primary sensory neurons, in vitro.
• Familiarity with calcium channels and their role in neuronal function is highly desirable but not required.
• Strong publication record in relevant fields (e.g., ion channel function in human and rodent nociceptors).
• Experience with managing projects and timeline, proactively identify potential research issues and troubleshooting.
• Able to train junior associates and productively manage project progress.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Willingness and ability to learn new methods and skills for changing research priorities.

See Table 13B for the salary range for this position. A reasonable estimate for this position is $93,400-$122,100.

Please apply online at: https://aprecruit.ucsf.edu/JPF05913 with a cover letter, CV, and contact information for two references. Applicant materials must list current qualifications upon submission.

Document requirements

• Cover Letter
• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
• Statement of Research (Optional)

Reference requirements

• 2 required (contact information only)