University of Cambridge

Neuroinflammatoy Mediators in the Pathophysiology of Traumatic Brain Injury

Closes: Dec 8, 2026

About the Project

Summary:

TBI is a complex disease with a number of underlying pathophysiological processes driven by mal-adaptive inflammation. Our group has related several pathological processes to specific inflammatory pathways, with a focus on identifying potential therapeutic targets.

Project Aims:

By integrating data from protein assays in biological fluids, Neuro-intensive care monitoring and patient outcomes, we will identify the underlying mechanisms that lead to brain swelling, raised intracranial pressure and neuronal injury.

Suitable for PhD

Funding Notes

For academic year October 27/28;

Gates US applications (round 1) close 14th October 26, further information available via Gates Website; View Website

Cambridge Trust, Gates Cambridge (round 2) deadline 8th December 26 to be eligible for funding. If you apply after the funding deadlines you will not be eligible for the Cambridge Funding competition, please indicate in your application all the funding you are eligible for. You can also check funding search Search - Postgraduate Funding Search

Funding is not available for Lent or Easter 27 places as the funding deadline for these has already passed, you will need to have other funding in place to support your studies

References

Ref: Inflammatory Mediators Related to Vascular Dysfunction are Linked to ICP, PRx, and CPP Following Human Severe Traumatic Brain Injury.
Smith CA, Lindblad C, Needham E, Beqiri E, Bergström S, Smielewski P, Nilsson P, Thelin E, Helmy A.
J Neurotrauma. 2025 Nov;42(21-22):1974-1984. doi: 10.1177/08977151251363979. Epub 2025 Aug 4.

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