"Open Rank Research Services Laboratory Sciences Professional (Entry or Intermediate)"

Job Summary

The overall focus of this translational research program is to better understand the unique adaptations governing pathological cardiac remodeling and the progression to heart failure in pediatric patients with complex congenital heart disease, including hypoplastic left heart syndrome and other single ventricle defects. This Laboratory Sciences Professional will have a key role in conducting a variety of experiments exploring the molecular and functional metabolic changes related to heart failure progression in this population. We utilize human tissue and blood samples in addition to cell culture- and murine- based models to conduct experiments evaluating molecular transcriptomic, proteomic, and functional alterations associated with heart failure progression. This work will be important for the identification and development of drug therapies that improve cardiac function and enhance transplant-free survival in a population with few other options.

Key Responsibilities:

• Cell culture.
• In vivo and ex vivo murine model work.
• Human blood sample processing.
• Molecular and cell biology techniques (RNA, DNA, protein, enzyme activity).
• Mitochondrial metabolic function assessment (Seahorse, Oroboros O2K).
• General laboratory maintenance, including reagent preparation, ordering, organization, and inventory cataloging.

Why Join Us

With an abundance of sunshine and mountains nearby, the Colorado Front Range is the place to be! The University of Colorado Denver, Anschutz Medical Campus as a whole, ranks among the top 20 medical centers in the country. CU Anschutz has top ranked clinical programs in family medicine and pediatrics, and the basic science and applied health research programs attract more NIH funding than any other university in Colorado. CU-Anschutz is home to the University of Colorado Hospital, The Children's Hospital of Colorado, and the University of Colorado Schools of Medicine, Nursing, Dentistry, Pharmacy and Pharmaceutical Sciences, and Public Health, providing access to an array of possibilities to improve lives across a spectrum of ages and disease states.

Across several labs at Children's Hospital Colorado and the Anschutz Medical Campus, teams of researchers, including ours, are investigating the early heart from an ever-growing array of angles, with the ultimate goal of developing the critical knowledgebase and infrastructure necessary to identify efficacious therapies to improve outcomes in pediatric patients. The Pediatric Heart Tissue and Blood Bank is one of the largest pediatric biobanks in the country, and serves as an incredible resource for these translational studies.

The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off – vacation, sick, and holidays and more. To see what benefits are available, please visit: https://www.cu.edu/employee-services/benefits-wellness.

Diversity and Equity

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications

Minimum Qualifications

Entry Level:
Bachelor's degree in biology, molecular biology, chemistry, genetics or related field.
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis.

Intermediate Level:
Bachelor's degree in biology, molecular biology, chemistry, genetics or related field.
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis.
One (1) year professional level research experience.

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications

• Master's degree in biology, molecular biology, chemistry, genetics or related field.
• Two (2) years of experience in an experimental or wet laboratory.
• Cell culture experience.
• Training in molecular techniques with a good theoretical understanding and experience in interpretation of results.
• Experience using rodent models.
• Laboratory management skills.

Knowledge, Skills and Abilities

• Proficient knowledge of basic laboratory techniques including safety procedures and techniques.
• Ability to communicate effectively, both in writing and orally.
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
• Outstanding customer service skills.
• Demonstrated commitment and leadership ability to advance diversity and inclusion.
• Knowledge of basic human anatomy, physiology medical terminology.
• Ability to interpret and master complex research protocol information.

How to Apply

For full consideration, please submit the following document(s):
1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
2. Curriculum vitae / Resume
3. Three to five professional references including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Anastacia (Tasha) Garcia, PhD (Anastacia.Garcia@CUAnschutz.edu)

Screening of Applications Begins

Applications will be accepted until finalists are identified, but preference will be given to complete applications received by December 15th, 2022. Those who do not apply by this date may or may not be considered.

Anticipated Salary Range

The hiring range for this position has been established at:
Entry Level – $40,280 to $51,236
Intermediate Level – $43,834 to $55,757

The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
This position may be eligible for overtime compensation depending on the level.
Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Total Compensation Calculator: http://www.cu.edu/node/153125

Job Category: Research Services
Primary Location: Aurora
Department: U0001 -- DENVER & ANSCHUTZ MED CAMPUS - 20980 - SOM-PEDS Cardiology-GenOps
Schedule: Full-time
Posting Date: Nov 17, 2022
Unposting Date: Ongoing
Position Number: 00804665