understanding how changes in protein structure control biological function. The project will focus on the biochemical and structural characterization of voltage-gated ion channels and its regulation by nanoantibodies in disease signaling pathways.
The lab is located within the University of Colorado School of Medicine Department of Physiology & Biophysics and the Aurora/Denver Anschutz Medical campus. Postdoctoral fellows will benefit from a multidisciplinary, vibrant, open, and collegial department. The Fernández-Mariño lab provides rich opportunities to interact with other biophysics and physiology laboratories within the department, also with an even larger collection of systems neuroscience laboratories studying the neural basis of sensory-motor behaviors.
Supervision Received
The Postdoctoral Fellow will be supervised by Dr. Ana Fernández-Mariño, Ph.D.
Examples of Work Performed
- Perform experiments and tabulate and analyze research data
- Oral communication of preliminary results at lab meetings
- Oral and written communication of completed work at national or international meetings.
- Create figures and write papers
- Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions
- Utilize a variety of laboratory techniques required for research projects
- Independently and creatively identify laboratory solutions
- Independently review, develop and implement new or modified laboratory techniques required for research projects
- Provide laboratory science expertise and leadership in study design, study oversight, data management, data analysis and manuscript preparation to assist all levels of investigators, researchers and clinicians on new research activities across a wide range of disciplines
Work Location:
Onsite – this role is expected to work onsite and is located in Aurora, CO.
Why Join Us:
Why work for the University?
The University of Colorado offers a comprehensive benefits package. To see what benefits are available for Post-Doctoral Fellows, please visit:
Qualifications:
Minimum Requirements:
Applicants must meet minimum qualifications at the time of hire.
Minimum requirements must be identifiable from the CV/Resume
- Ph.D. in biochemistry, structural biology, molecular biology, biophysics, neuroscience, or a related field
- A record of first-author publications
Preferred Qualifications:
Identifiable from the CV/Resume
- Experience with any of the following:
- Molecular Biology
- Expression and purification of recombinant proteins
- Membrane protein production and characterization
- Protein engineering and biochemical assay development
- Nanobody discovery, selection, characterization
- Structural biology approaches (preferably cryo-EM)
- Biophysical characterization of protein structure
- Experience with membrane proteins and/or nanobody technologies is highly desirable. Expertise in structural biology would be a major advantage, but enthusiasm for learning new approaches and addressing challenging biological questions is equally valued.
Knowledge, Skills, and Abilities:
- Advanced knowledge of laboratory techniques including safety procedures and techniques
- Ability to communicate effectively, both in writing and orally
- Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
- Ability to interpret and master complex research protocol information
- Knowledge on molecular biology
- Knowledge on basic animal anatomy and physiology.
How to Apply:
For full consideration, please submit the following document(s):
- A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
- Curriculum vitae / Resume
- Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address
Applications are accepted electronically ONLY at www.cu.edu/cu-careers.
Questions should be directed to: ANA.FERNANDEZ-MARINO@CUANSCHUTZ.EDU
Screening of Applications Begins:
Applications will be accepted until finalists are identified, but preference will be given to complete applications received by August 31, 2026. Those who do not apply by this date may or may not be considered.
Anticipated Pay Range:
The starting salary range (or hiring range) for this position has been established as HIRING RANGE:
$63,480 - $67,000
The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.
Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Total Compensation Calculator: http://www.cu.edu/node/153125
