Post-Doctoral Research Fellow

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Simon Lab at Fred Hutch seeks a highly skilled Post-Doctoral Research Fellow to define principles for successful adoptive transfer of genetically modified Chimeric TCR T cells, with a focus on engineering synthetic T cell signaling circuits to instruct T cells with optimized functions for cancer therapy.

Responsibilities

To drive a project to develop the next generation of highly sensitive and multi-specific T cell receptors for adoptive cell transfer immunotherapies of blood cancers and solid tumors with the goal to prevent relapses in treated patients. The incumbent will lead a project independently while mentoring and directing junior members of the team under the PI's supervision.

Job Duties:

• Handling projects independently, including literature reviews, experimental design, and data analysis, under the guidance of the laboratory PI.
• Contributing to the preparation of research reports, publications, and oral presentations.
• Stay current with relevant publications and apply knowledge to research.
• Compile data and synthesize innovative problem-solving methods.
• Collaborate and present data with a wide range of stakeholders and partners.
• Opportunities for presentations at scientific conferences and symposiums.
• Mentor and lead undergraduate and graduate students.
• Assist with lab maintenance and function.

Qualifications

MINIMUM QUALIFICATIONS:

• MD and/or a PhD in a biological science with a diverse knowledge of immunology
• Proficient in immunology techniques and know-how
• Strong scientific writing skills, ability to write and apply for funding opportunities and abstracts
• Able to digest complex material and synthesize innovative ideas
• Compile and clearly present data to an eclectic audience, both orally and written
• Strong understanding of T cell biology and signaling is required
• Demonstrate strong capacities to lead tool and technology development to interrogate biology

PREFERRED QUALIFICATIONS:

• Experience in gene editing, proteomics and microscopy.
• Strong publication record

The annual base salary range for this position is from $80,172 to $95,014, and pay offered will be based on experience and qualifications.