"Post-Doctoral Research Fellow"

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

A Post-Doctoral Research Fellow training position is available to study the molecular mechanisms underlying cancer treatment resistance and the development of new therapeutics. The training will be mentored by Dr. Michael Haffner and members of his research group.

Training opportunities are provided through a highly multi-disciplinary research team that includes scientists with expertise in biochemistry, bioinformatics, single cell genomics, epigenetics, pharmacology and pathology. The laboratory website provides additional information: https://research.fredhutch.org/haffner/en.html

Responsibilities

The particular areas of emphasis for this position center on studies of resistance to current therapeutics deployed to treat advanced cancer including therapeutics that exploit DNA repair deficiency and immune-based agents. We are recruiting a Post-Doctoral Fellow to engage in laboratory-based studies of these processes. This position will focus on delineating the molecular mechanisms driving treatment resistance that include cell intrinsic (e.g. mutation, tumor heterogeneity, cell plasticity, epigenetic) and microenvironment events, with opportunities for translational studies evaluating new clinical approaches that circumvent resistance mechanisms. The research has direct relevance to the treatment of cancer patients.

Qualifications

MINIMUM QUALIFICATIONS:

• Ph.D. or M.D. in biology; biochemistry; genetics; molecular biology; cell biology; immunology or related field.
• Experience in one of the following areas is required:
  • Medicine/Urology
  • Genomics/Genetics
  • Analysis of inflammation/Immune composition
  • Biomarker characterization
• Highly motivated and organized. Thinks independently but enjoys working as part of a dynamic, collaborative, and multidisciplinary team.
• Excellent verbal and written communication skills.

PREFERRED QUALIFICATIONS:

• Expertise in computational biology. Demonstrated proficiency in RNA-seq and single cell RNA-seq analyses.
• Expertise/skills in molecular biology techniques: RT-PCR, immunohistochemistry, ELISA, cell culture, drug toxicity assays.
• Strong publication record with high impact first author paper

The annual base salary range for this position is from $77,976 to $95,014, and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance. Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).