Postdoctoral Fellow, Cancer Biology and Bioinformatics, Kasper Lab Department

About the Department

As one of the oldest medical schools in the country, the University of Cincinnati College of Medicine (COM) has a reputation for training best-in-class healthcare professionals and developing cutting-edge procedures and research that improve the health and clinical care of patients. In partnership with the UC Health academic healthcare system and Cincinnati Children?s Hospital Medical Center, the College of Medicine?s faculty are transforming the world of medicine every day.

Cincinnati is a vibrant city with affordable housing and low cost of living, with an internationally oriented varied community. Good schools and world-class cultural activities provide an excellent backdrop from which to engage in cutting-edge research.

Job Overview

One full-time staff position is available in the laboratory of Dr. Susan Kasper in the Department of Environmental & Public Health Sciences, College of Medicine, University of Cincinnati.

The Kasper Laboratory integrates human primary cancer cell culture, cancer stem cell biology, mouse xenograft models, and most recently extracellular vesicles in collaboration with Dr. Somchai Chutipongtanate with multiomics technologies and bioinformatics to investigate mechanisms of prostate cancer progression and metastasis. A leading focus is on mechanisms that drive cancer cell growth and metastasis, in particular cancer cell/tumor microenvironment interactions that regulate these processes via signals carried by extracellular vesicles, and to establish prognostic and predictive biomarkers of metastasis. Additional information or questions regarding the project can be obtained by email at susan.kasper@uc.edu

We are seeking an enthusiastic and highly self-motivated candidate who can work both independently and cooperatively as part of a team. Candidates with a strong background in cancer biology, molecular biology, and bioinformatics are encouraged to apply. This position involves a focus on secretomes and extracellular vesicles, single-cell sequencing analysis, and investigating the molecular mechanisms of prostate cancer metastasis and its interaction with stromal cells in the tumor microenvironment.

Essential Functions

• Conduct cutting-edge research on prostate cancer metastasis, focusing on molecular mechanisms, post-translational phosphorylation, and cell-cell interactions within the tumor microenvironment.
• Investigate the roles of secretomes and extracellular vesicles in cancer progression
• Utilize advanced bioinformatics tools and single-cell sequencing technologies to analyze complex datasets.
• Collaborate with a multidisciplinary team of scientists and researchers.
• Specific for the postdoctoral position: Disseminate research findings through publication in high-impact journals and presentations at international conferences.

Required Education

Doctoral degree in Molecular Medicine, Cancer Biology, or a closely related field

Required Experience

Significant skills in assays for flow cytometry, Image stream, bioassays, cellular transfections, primary cell culture from clinical biopsy samples, bioinformatics, including single-cell or spatial sequencing analyses. Excellent analytical, organizational, and communication skills. Ability to work collaboratively in a multidisciplinary team environment. Specific for the postdoctoral position: a proven track record of scientific publications in relevant fields.

Physical Requirements/Work Environment

Office environment/no specific unusual physical or environmental demands.