Position Description
The Wyss Institute for Biologically Inspired Engineering at Harvard University seeks outstanding postdoctoral applicants with expertise in immunology and computational biology, specifically bulk/single cell sequencing and AI/ML workflows, to join an interdisciplinary team of biologists and engineers to leverage in vitro organ-on-a-chip (Organ Chip) microfluidic culture systems and injectable formulations to study and model adaptive immunity in female reproductive tract cancers.
What you'll do:
- Integrate multi-omics, spatial pathology, and clinical datasets to identify biomarkers of therapy responsiveness, define cancer patient subpopulations most likely to benefit from therapy, and support biomarker-informed clinical translation.
- Develop, use, and evolve computational pipelines, including for: Analysis of bulk and single cell RNA-sequencing, spatial transcriptomics, and proteomics datasets; Integration of experimental model data with public and clinical datasets; Statistical modeling and survival analysis; Machine learning and retrieval-augmented AI models for biomarker prioritization and decision support
- Work closely with cross-functional team members to develop hypotheses, interpret data, and advance project goals
- Work closely with the organ chip bench team to assist and/or independently design, develop, and execute in vitro experimental protocols; generate robust and consistent data of high quality with clear scientific documentation
- Present key results to project teams and stakeholders.
- Contribute to grants, publications, and patent applications.
- Mentor students and technicians and provide project feedback.
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