"Postdoctoral Position in Polycystic Kidney Disease Research at Qian Lab"

Job title:

Postdoctoral Position in Polycystic Kidney Disease Research-
Qian Lab

Job description:

Applicants are sought for a two-year, potentially extendable,
full-time postdoctoral position in the laboratory of Dr. Feng Qian
investigating molecular mechanisms underlying polycystic kidney
disease (PKD). PKD is the most common genetic cause of renal
failure. It is caused by mutations in PKD1, PKD2 or
PKHD1 genes, which encode polycystin-1, -2 or
fibrocystin/polyductin, respectively. The laboratory is located in
the new state-of-art Health Sciences Facility III Building on the
campus. It is a part of the Baltimore PKD Research Center supported
by the NIH R01 grants and U54 PKD Research Consortium (https://www.pkd-rrc.org/about-pkd-rrc/).

The postdoctoral researcher will join a group studying PKD with
biochemical, biophysical, cell biological, systems biology methods
and mouse models etc. The researcher will primarily be involved in
a project investigating the role of polycystins complex as a
distinct ion channel and in primary cilia in kidney physiology and
disease. The project will also involve the functional regulation of
polycystin-1 by the cleavage at the G-protein coupled receptor
proteolysis site (GPS) motif, a key posttranslational modification
of the protein, in cell signaling. The laboratory is highly
collaborative with many opportunities to contribute to other,
related ciliopathy projects.

Qualifications:

Requirements include a Ph.D. (or equivalent) in cellular and
molecular biology or related disciplines. Desirable skills include
experience with mouse experimentation, histology, microscopy, cell
culture, biochemistry, cell signaling, and molecular biology
methods.

UMB is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law or policy. For assistance related to employment, please contact the Staffing department at HRJobs@umaryland.edu.