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University of Oxford

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Centre for Human Genetics, Old Road Campus, Roosevelt Drive, Oxford, OX3 7BN

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"Postdoctoral Research Assistant"

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Postdoctoral Research Assistant

Research Grade 7

16 March 2026 12:00

Location

Centre for Human Genetics, Old Road Campus, Roosevelt Drive, Oxford, OX3 7BN

University of Oxford

Type

Full-time fixed-term (1 year)

Salary

£39,424 - £46,476

Required Qualifications

PhD/DPhil in relevant discipline
Endothelial cell culture
Molecular biology (cloning, confocal imaging, biochemical assays)
SDS-PAGE & Western blotting
qPCRs
Fluidics/shear stress assays
First-author publication (not review)

Research Areas

Mechanotransduction
Cardiovascular disease
Atherosclerosis
Fluidics
Endothelial biology
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Postdoctoral Research Assistant

Postdoctoral Research Assistant

Location: RDM Division of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, OX3 9DU

We are seeking a highly motivated Postdoctoral Research Assistant with expertise and interest in Cell Biology/Physiology/Cardiovascular Science to join the Tzima research group at the Centre for Human Genetics in Oxford.

The Tzima research group investigates the role of mechanotransduction in cardiovascular disease and the laboratory is at the cutting edge of developments in in vitro and in vivo models of mechanotransduction. Research projects are highly interdisciplinary, aiming to integrate in vitro biochemical and cell biological techniques with in vivo models and clinical samples. Recent publications from the group include Nature, Science Advances, J Cell Biology. We are looking for a highly motivated Postdoctoral Research Scientist to join the group to work in the area of mechanotransduction, fluidics to characterise the role of a novel gene in atherosclerosis development and progression. You will become part of the Division of Cardiovascular Medicine based at the Centre for Human Genetics in Oxford.

The post-holder is required to hold a PhD/DPhil in a relevant discipline and will carry out independent research exploring fundamental mechanisms of mechanotransduction and its role in cardiovascular disease. You will have proven experience in endothelial tissue cell culture, molecular biology techniques including cloning, confocal imaging and biochemical assays (SDS-PAGE and Western blotting, qPCRs). Experience with fluidics systems especially shear stress assays is also required. It is also essential that the applicant has published a first author publication (accepted or in press is also acceptable) that is not a review.

This is a full-time appointment on a fixed term contract for 1 year in the first instance, and you will be based at the Centre for Human Genetics, Old Road Campus, Roosevelt Drive, Oxford, OX3 7BN.

Applications for this vacancy are to be made online; you will be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post.

Only applications received before 12.00 midday on 16th March 2026 can be considered. Interviews are due to take place on 30th March 2026.

The University of Oxford offers an attractive range of competitive benefits available to all staff for both work and personal life - https://hr.admin.ox.ac.uk/staff-benefits

For informal enquiries about the post, please contact Ellie Tzima – ellie.tzima@cardiov.ox.ac.uk Georgia Broom – cvm_personnel@cardiov.ox.ac.uk

The University is an Equal Opportunity Employer

Pay Scale: RESEARCH GRADE 7

Salary (£): 39424 - 46476

Contact Person: Professor Ellie Tzima

Vacancy ID: 184745

Closing Date & Time: 16-Mar-2026 12:00

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Frequently Asked Questions

🎓What qualifications are required for this Postdoctoral Research Assistant role?

The post requires a PhD/DPhil in a relevant discipline such as Cell Biology, Physiology, or Cardiovascular Science. Essential experience includes endothelial cell culture, molecular biology techniques (cloning, confocal imaging, biochemical assays like SDS-PAGE, Western blotting, qPCRs), and fluidics systems especially shear stress assays. A first-author publication (accepted or in press, not a review) is mandatory. Learn how to thrive in postdoctoral roles.

🔬What is the research focus of this position?

Join the Tzima research group to investigate mechanotransduction in cardiovascular disease, using in vitro, in vivo models, and clinical samples to characterize a novel gene in atherosclerosis development. Interdisciplinary work integrates biochemical, cell biological techniques with fluidics. Recent publications in Nature, Science Advances, J Cell Biology. Explore research assistant success tips.

📝How do I apply for this University of Oxford postdoc?

Applications must be made online, uploading a CV and supporting statement explaining how you meet the selection criteria. Only submissions before 12:00 midday on 16 March 2026 are considered. Interviews on 30 March 2026. Prepare your academic CV effectively.

💰What is the salary and contract details?

Salary on Research Grade 7: £39,424 - £46,476. Full-time, fixed-term for 1 year in the first instance, based at Centre for Human Genetics, Oxford. University offers competitive benefits; see staff benefits.

📧Who should I contact for informal enquiries?

Contact Professor Ellie Tzima at ellie.tzima@cardiov.ox.ac.uk or Georgia Broom at cvm_personnel@cardiov.ox.ac.uk for informal discussions about the mechanotransduction project in cardiovascular medicine. Read advice on attracting top talent in academia.
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