Question 1

What qualifications are required for this Postdoctoral Research Associate in Cryo-EM role?

Accepted Answer

You must hold or be near completion of a PhD/DPhil in Biochemistry , Molecular Biology , Molecular Genetics , or a related discipline. Essential experience includes using single-particle cryo-electron microscopy to solve biological problems, plus protein expression , purification , and biochemical assays . Skills in molecular biology , genetics , and DNA-binding proteins are beneficial. Explore more postdoc opportunities or postdoctoral success tips .

Question 2

What is the research focus of this Cryo-Electron Microscopy DNA Repair position?

Accepted Answer

The project investigates bacterial DNA repair mechanisms for protein-DNA crosslinks induced by fluoroquinolone antibiotics, focusing on the exonuclease VII (Exo7) repair complex. You'll use structural biology and biochemistry to study how Exo7 processes crosslinks from stalled type II topoisomerases, contributing to antimicrobial resistance (AMR) . Coordinated with live-cell imaging in Prof Stephan Uphoff's lab. Learn about research jobs in this area.

Question 3

How do I apply for this University of Oxford Postdoc in Structural Biology?

Accepted Answer

Apply online via www.recruit.ox.ac.uk using Vacancy ID 185636 . Upload your CV and a supporting statement addressing selection criteria. Provide two referees. See advice on supporting statements . Check free resume templates and career advice for academics.

Question 4

What salary, benefits, and contract details are offered?

Accepted Answer

Salary: £42,794 - £47,779 per annum (Grade 7). Full-time ( 37.5 hours/week ), fixed-term up to 3 years , funded by BBSRC . Benefits include excellent pension, 38 days annual leave , childcare, family leave, cycle loans, sports clubs, and discounted travel. View university salaries for comparisons.

Question 5

What facilities are available for this Cryo-EM research role at Oxford?

Accepted Answer

Work in a modern lab for protein purification , microbiology, and molecular biology. Access COSMIC cryo-EM facility with 200 kV Talos Arctica (Falcon 4i) and 300 kV Krios (K3 detector, energy filter). Additional University facilities: biophysical suite, proteomics, mass photometry, native MS. Ideal for structural biology of DNA repair proteins . See related research roles .

Question 6

When is the application deadline and what happens next?

Accepted Answer

Closing date: 12:00 noon, Monday 18th May 2026 . Only timely applications considered. Interviews for shortlisted candidates as soon as possible thereafter. Contact recruitment@bioch.ox.ac.uk for enquiries. Prepare with research assistant tips adaptable to UK roles.

Postdoctoral Research Associate in Cryo-Electron Microscopy of DNA Repair Proteins

University of Oxford

Dorothy Crowfoot Hodgkin Building, Biochemistry Department, South Parks Road, Oxford, OX1 3QU

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