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Dorothy Crowfoot Hodgkin Building, Biochemistry Department, South Parks Road, Oxford, OX1 3QU

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"Postdoctoral Research Associate in the Molecular Analysis of Bacterial Outer Membrane Protein Biogenesis"

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Postdoctoral Research Associate in the Molecular Analysis of Bacterial Outer Membrane Protein Biogenesis

Postdoctoral

9 March 2026, 12:00 noon

Location

Dorothy Crowfoot Hodgkin Building, Biochemistry Department, South Parks Road, Oxford, OX1 3QU

University of Oxford

Type

Full-time, Fixed-term (up to 3 years)

Required Qualifications

PhD/DPhil in Biochemistry or Molecular Microbiology
Expertise in membrane protein purification/characterization
Bacterial protein characterization
Recombinant DNA techniques
Molecular bacteriology (advantageous)

Research Areas

Bacterial outer membrane protein biogenesis
Structure-function studies
Proteomics
High-throughput genetic analysis
Protein transport
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Postdoctoral Research Associate in the Molecular Analysis of Bacterial Outer Membrane Protein Biogenesis

About the role

We are seeking to appoint two talented Postdoctoral Research Associates to undertake complementary projects investigating bacterial outer membrane protein biogenesis in the group of Prof Ben Berks FRS.  Building on our recent work in this area (Nature (2015) 647: 479-487) you will carry out structure-function and molecular bacteriological studies using a range of approaches including protein purification, in vitro and cellular protein characterization, proteomics, and high throughput genetic analysis. Structural studies will be carried out in collaboration with Prof. Susan Lea FRS FMedSci at St. Jude Children’s Research Hospital, and the successful candidates will have the opportunity to spend periods at St. Jude in Memphis, USA.

Candidates will be interviewed for both posts through a single interview process. The successful candidates will have their own distinct projects but should also be prepared to work closely with each other and other group members working on Bacteroidota cell envelope processes.

These full-time fixed-term posts are funded by the European Research Council for up to 3 years in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

About you

You should hold, or be near completion of, a PhD/DPhil in Biochemistry, Molecular Microbiology, or related discipline. You must have proven and substantive expertise in the purification and characterization of membrane proteins, in protein characterization in a cell biology context especially in bacteria, and in recombinant DNA techniques. Proven and substantive experience in any of the following would be advantageous: molecular bacteriology including the construction of chromosomal mutations in bacteria; isolation of proteins expressed at native levels; proteomics and the analysis of proteomics data; high throughput genomic methods; the investigation of protein transport or membrane protein biogenesis. You will be highly organised with the ability to work both independently and as part of a team and have good communication skills. A good publication record in areas relevant to the project is expected, taking career stage into account.

What We Offer

Your happiness and wellbeing at work matters to us, so we offer a range of family friendly and financial benefits including:

  • An excellent contributory pension scheme
  • 38 days annual leave
  • A comprehensive range of childcare services
  • Family leave schemes
  • Cycle loan scheme
  • Membership to a variety of social and sports clubs
  • Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

Application Process

Applications for this vacancy are to be made online via www.recruit.ox.ac.uk and Vacancy ID 184728. You will be required to upload your curriculum vitae and a supporting statement, setting out how you meet the selection criteria for the post, using examples of your skills and experience. Click here for information and advice on writing an effective Supporting Statement. As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now.

For further details, please refer to the How to apply section of the job description. Any further enquires may be directed to recruitment@bioch.ox.ac.uk.

The closing date for applications is 12.00 noon on Monday 9th March 2026. Only applications received before this time can be considered. Interviews for shortlisted candidates to be held as soon as possible thereafter.

Committed to equality and valuing diversity

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Frequently Asked Questions

🎓What qualifications are required for this Postdoctoral Research Associate position?

Candidates must hold or be near completion of a PhD/DPhil in Biochemistry, Molecular Microbiology, or related discipline. Proven expertise in membrane protein purification and characterization, bacterial protein analysis, and recombinant DNA techniques is essential. Advantageous skills include molecular bacteriology, proteomics, and high-throughput genomics. See academic CV tips for applications.

🔬What does the research involve in bacterial outer membrane protein biogenesis?

Projects focus on structure-function and molecular bacteriological studies using protein purification, in vitro/cellular characterization, proteomics, and high-throughput genetics. Building on recent Nature publication. Collaboration with Prof. Susan Lea at St. Jude Children’s Research Hospital; opportunities for US visits. Explore postdoc success strategies.

📝How to apply for this Oxford Biochemistry postdoc?

Apply online via www.recruit.ox.ac.uk (Vacancy ID 184728). Upload CV and supporting statement addressing selection criteria. Provide two referees. Closing date: 9 March 2026, 12:00 noon. Single interview for both posts. Guidance: CV and supporting statement advice.

💼What benefits does University of Oxford offer these postdocs?

Full-time fixed-term up to 3 years, ERC-funded. Benefits include excellent pension, 38 days annual leave, childcare services, family leave, cycle loans, social/sports clubs, discounted travel. Strong publication record expected. Review postdoc wellbeing tips.

🌍Are there opportunities for international collaboration?

Yes, structural studies with Prof. Susan Lea FRS at St. Jude Children’s Research Hospital, Memphis, USA. Successful candidates can spend periods there. Work closely with group on Bacteroidota envelope processes. Ideal for postdoctoral researchers seeking global exposure.

What is the closing date and interview timeline?

Applications close 12:00 noon, Monday 9 March 2026. Interviews as soon as possible thereafter. Only timely applications considered. Enquiries: recruitment@bioch.ox.ac.uk.
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