"Postdoctoral Research Associate--Translational/Muscle Biology (Murine Models)"

About the Opportunity

We are seeking a highly motivated Postdoctoral Research Associate to join the New England Inflammation and Tissue Protection Institute and contribute to early-stage efforts focused on muscle biology and inflammatory disease. The successful candidate will apply their expertise in murine models and immunology to explore disease mechanisms, validate novel therapeutic targets, and support highly translational research initiatives.

Key Responsibilities

• Experimental Design & Execution: Develop and execute in vivo studies using murine models to investigate translational mechanisms in muscle biology and inflammatory disorders.
• Model Development: Contribute to the design and characterization of disease-relevant murine models, including biochemical and pharmacological manipulations.
• Assay Development: Support the development of cellular and biochemical assays to complement in vivo findings.
• Data Analysis & Interpretation: Analyze complex datasets from in vivo and in vitro experiments; present findings to cross-functional teams and industrial biotech. partners.
• Collaboration: Work closely with scientists across disciplines including immunology, molecular biology, and bioinformatics to integrate findings.
• Scientific Communication: Publish results in peer-reviewed journals and present at internal and external scientific meetings.

Qualifications and Skills

• PhD in cellular biology, molecular biology, biochemistry, immunology, or related field, with a strong focus on murine myopathy models.
• Demonstrated experience in in vivo experimentation, including animal handling, dosing, tissue collection, and phenotypic analysis.
• Familiarity with translational assays and molecular techniques (e.g., Multiparameter Flow Cytometry, Immunohistochemistry, Histology, ELISA, ELISPOT, Incucyte, qPCR, Western blot)
• Strong in vitro skills including immune cell and co-culture assays, cell-based immunological assays, inflammatory models.
• Strong analytical skills and attention to detail.
• Excellent communication, work ethic, and interpersonal and team leadership skills.
• A track record of scientific publications in relevant fields.
• Experience with models of myopathies or inflammation.
• Familiarity with stem cell-derived muscle models or 3D culture systems (including physiological hypoxia) is a plus.
• Experience in biochemical and immunological mechanisms of immune-suppression

Position Type

Research

Additional Information

Northeastern University considers factors such as candidate work experience, education and skills when extending an offer.

Northeastern has a comprehensive benefits package for benefit eligible employees. This includes medical, vision, dental, paid time off, tuition assistance, wellness & life, retirement- as well as commuting & transportation. Visit https://hr.northeastern.edu/benefits/ for more information.

All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, religion, color, national origin, age, sex, sexual orientation, disability status, or any other characteristic protected by applicable law.