Postdoctoral Researcher in Myeloid Neoplasms (MPNs) and Blast Phase MPN

University of Oxford - MRC Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit

Location: John Radcliffe Hospital, Headington, Oxford OX3 9DS

We are seeking a talented and motivated researcher to join the Mead Group to contribute to a major research programme focused on understanding and preventing disease progression in myeloproliferative neoplasms (MPNs). The role would suit an ambitious, proactive and detail-oriented individual, with experience in haematopoieses research, molecular biology and genomics, with a passion for applying their skills to improve patient outcomes through impactful biomedical research.

You will take a lead role in conducting wet lab experimentation, applying state-of-the-art single-cell multiomic approaches and functional genomic screens to patient-derived samples and disease models. Working closely with a dynamic and multidisciplinary team of clinicians and scientists, you will help generate and interpret high-resolution datasets that reveal new insights into disease progression, with the ultimate aim of identifying novel biomarkers and therapeutic targets.

You will hold a relevant PhD/DPhil, together with sufficient specialist knowledge in normal and malignant haematopoiesis research. Experience of molecular biology, single cell gemonics and/or spatial transcriptomics techniques and data analysis will be essential, together with first author high-impact papers in the field of leukaemia biology.

The post is available fixed-term until 31 December 2028, funded by Cancer Research UK.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

The closing date for this position is 12:00 noon on Monday 16 February 2026.

Interviews will be held on Monday 2 March 2026.