"Research Associate 1"

Overview

The Research Associate will be working on the studies on the immune profiling of children and adults with high risk conditions such as sickle cell disease. Our group conducts lab based and epidemiological studies to assess vaccine immunogenicity, efficacy and effectiveness for different vaccines. We utilize multicolor flow cytometry and CyTOF to interrogate innate immune pattern recognition receptor (PRR) function. We use in-depth single cell profiling from whole blood analysis of age-related chronic inflammation to evaluate Toll-like Receptor (TLR), RIG-I, and NLRP3 function at baseline and following ex vivo stimulation with specific PRR ligands. We also assess the expansion of T-cell and B-cell subsets following vaccination, including in vitro stimulation with vaccine strains to identify antigen-specific responses.

The Research Associate will perform independent research and laboratory techniques and participate in experimental research planning. Will work independently to develop manage and organize multi-site studies. Ensures data results are compiled, analyzed, and presented properly. Will supervise and train other team members and students on study related tasks including flow cytometry and analysis.

Required Skills and Abilities

1. Demonstrated track record of proficiency in flow cytometry and/or biostatistic analysis. Familiarity with statistical analysis software (e.g., SPSS, SAS, R)
2.  Ability to Analyze, develop and interpret scientific results. Maintains clear documentation of results. Prepares scientific reports and papers for research proposals and published reports.
3. Ability to Coordinate with internal contacts including the PI, research assistants, graduate students, Radiation Safety and Biological Safety officers.

Preferred Skills and Abilities

Master's degree in public health preferred.

Principal Responsibilities

1. Recommends the design and implementation of procedures and protocols under the direction of a higher-level authority. 2. Investigates, analyzes, and reaches preliminary scientific conclusions related to research planning 3. Ensures data results are compiled, analyzed, and presented properly. 4. Analyzes, develops and interprets scientific results. Maintains clear documentation of results. Prepares scientific reports and papers for research proposals and published reports. 5. Performs independent research and laboratory techniques and participates in experimental research planning. 6. Interacts with internal contacts including the PI, research assistants, graduate students, Radiation Safety and Biological Safety officers, and Animal Care personnel to discuss and evaluate research results and to ensure the smooth and safe operation of the laboratory. 7. Interacts with external contacts such as researchers at other institutions, staff at biotechnology and reagents companies to consult on research methods and to keep abreast of product information and developments. 8. May perform other duties as assigned.

Required Education and Experience

Master’s Degree in a scientific discipline and one year experience or an equivalent combination of education and experience.