University of Cambridge  Jobs

University of Cambridge

Applications Close:

The Old Schools, Trinity Ln, Cambridge CB2 1TN, UK

5 Star Employer Ranking

"Research Associate (Fixed Term)"

Academic Connect
Applications Close
Is this job right for you? View Vital Job Information and Save Time

Research Associate (Fixed Term)

Research Associate

2027-05-25

Location

Island Research Building, Cambridge Biomedical Campus, CB2 0AH, UK

University of Cambridge

Type

Fixed-term

Required Qualifications

PhD (or near completion)
Protein degradation research experience
Neurodegenerative diseases knowledge

Research Areas

E3 ubiquitin ligases
Tau aggregates degradation
TRIM21 antiviral receptor
Neurodegenerative diseases
71% Job Post Completeness

Our Job Post Completeness indicates how much vital information has been provided for this job listing. Academic Jobs has done the heavy lifting for you and summarized all the important aspects of this job to save you time.

Research Associate (Fixed Term)

Research Associate (Fixed Term)

We are seeking to appoint a Research Associate to join the McEwan Group at the UK Dementia Research Institute at the University of Cambridge.

The post is a fixed term study in collaboration with the ARUK Drug Discovery Institute.

The successful candidate will research the ability of E3 ubiquitin ligases to degrade cytosolic protein aggregates in neurodegenerative diseases. They will build from recent discoveries that the antiviral receptor TRIM21 can evoke a potent degradation response against tau (Benn et al 2024 39208111), to uncover the range and requirement of ligases that can drive aggregate responses. Newly identified ligases will become the subject for collaboration with DDI for medicinal chemistry approaches.

For informal inquiries regarding the role, contact Dr William McEwan wm305@cam.ac.uk The role will be based at the UK DRI, Island Research Building Cambridge Biomedical Campus, CB2 0AH

The University values diversity and is committed to equality of opportunity. We particularly encourage women and/or candidates from a Black, Asian and Minority Ethnic background to apply for this vacancy as they are currently under-represented at this level within our University.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Fixed-term: The funds for this post are available until 28 February 2027 in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Applicants must have (or be close to obtaining) a PhD.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38 £34,132) moving to Research Associate (Grade 7) upon confirmation of your PhD award.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference ZE45925 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

### Further information

Tell them AcademicJobs.com sent you!

Apply Now

Frequently Asked Questions

🎓What qualifications are required for this Research Associate position?

Applicants must have PhD or be close to obtaining one in a relevant field such as biochemistry or neuroscience. Appointment at Research Associate level (Grade 7) requires PhD confirmation; otherwise, start as Research Assistant (Grade 5, £34,132). Relevant experience in protein aggregates and ubiquitin ligases is essential. See postdoc success tips and academic CV guide.

🔬What is the research focus of this role at University of Cambridge?

The role investigates E3 ubiquitin ligases ability to degrade cytosolic protein aggregates in neurodegenerative diseases, building on TRIM21 discoveries against tau (Benn et al 2024). Identify new ligases for medicinal chemistry collaboration with ARUK Drug Discovery Institute. Explore research jobs in medicine.

📅What is the employment duration and type?

Fixed-term position with funds available until 28 February 2027. Full-time academic role in McEwan Group. University emphasizes diversity and encourages applications from underrepresented groups. Check postdoc opportunities.

📝How to apply for this Research Associate job?

Click "Apply" to register, upload covering letter (matching criteria), CV, and referee details (including recent line manager). Quote reference ZE45925. Further particulars PDF available. Informal inquiries to Dr William McEwan. Prepare with free cover letter template.

🌍Is visa sponsorship available, and what about location?

University requires eligibility to live/work in UK; no visa sponsorship mentioned. Based at UK DRI, Cambridge Biomedical Campus. Committed to equality of opportunity. Explore faculty jobs in UK and research assistant roles.

🤝What support is available for applicants?

Diversity encouraged, especially women and BAME candidates. Upload only requested documents. Referees must include email/phone. View higher ed career advice.
1 Jobs Found
View More