University of Cambridge  Jobs

Research Associate (Fixed Term)

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University of Cambridge

Cambridge Biomedical Campus, CB2 0AH

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Research Associate (Fixed Term)

Research Associate

23 April 2026

Location

Cambridge Biomedical Campus, CB2 0AH

University of Cambridge

Type

Fixed-term (36 months)

Salary

£37,694-£46,049

Required Qualifications

PhD (or close to obtaining)
Computational biology
Transcriptomics
Long-read/single-cell analysis
Neurodegenerative disease research

Research Areas

Transcript-specific regulation
Cell-type-selective gene expression
Neurodegenerative disease
RNA therapeutics
Single-cell transcriptomics
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Research Associate (Fixed Term)

Research Associate (Fixed Term)

We are seeking to appoint a Research Associate to join the Ryten Group at the UK Dementia Research Institute at the University of Cambridge.

This fixed-term post is available for 36 months.

The successful candidate will investigate transcript-specific regulatory mechanisms underlying cell-type-selective gene expression in neurodegenerative disease. The role will focus on defining how alternative promoter usage, transcription initiation, and transcript isoform diversity influence RNA regulation and downstream cellular phenotypes. Working within an interdisciplinary research programme integrating long-read and single-cell transcriptomics with translational RNA therapeutic development, the postholder will develop and apply novel computational approaches to identify regulatory features governing transcript expression in neuronal and glial systems. This work will contribute to mechanistic understanding of neurodegenerative disease biology and inform rational design of precision RNA-targeted therapeutic strategies.

For informal inquiries regarding the role, contact Professor Mina Ryten (mr2022@cam.ac.uk). The role will be based at the UK DRI, Island Research Building Cambridge Biomedical Campus, CB2 0AH.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Applicants must have (or be close to obtaining) a PhD.

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38 £34,610) moving to Research Associate (Grade 7) upon confirmation of your PhD award.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference RR49367 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Key information

Department/location

Department of Clinical Neurosciences

Salary

£37,694-£46,049

Reference

RR49367

Category

Research

Date published

9 April 2026

Closing date

23 April 2026

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Frequently Asked Questions

🎓What qualifications are required for this Research Associate position?

Applicants must have or be close to obtaining a PhD. Appointment at Research Associate level (Grade 7) requires PhD confirmation; those submitted but awaiting award start as Research Assistant (£34,610). Expertise in computational transcriptomics and neurodegenerative disease is essential. Learn more about research assistant jobs and postdoctoral success.

🔬What are the main responsibilities in the Ryten Group at UK DRI?

The role involves developing novel computational approaches to study transcript-specific regulatory mechanisms in neurodegenerative disease. Focus on alternative promoter usage, transcription initiation, and isoform diversity using long-read and single-cell transcriptomics. Contribute to RNA therapeutic development. Explore research jobs for similar opportunities.

📝How do I apply for this fixed-term Research Associate role?

Click the Apply button to register and submit online. Upload a covering letter explaining fit to criteria, CV, and referee details (including most recent line manager). Quote reference RR49367. Closing date: 23 April 2026. See free cover letter template and free resume template for tips.

💰What is the salary and employment duration?

Salary: £37,694-£46,049. This is a fixed-term post for 36 months at the UK Dementia Research Institute, University of Cambridge. Check professor salaries and university salaries for comparisons in higher ed.

📧Is visa sponsorship available, and who can I contact for inquiries?

The University requires eligibility to live/work in the UK; no explicit visa sponsorship mentioned. For informal inquiries, contact Professor Mina Ryten (mr2022@cam.ac.uk). Location: Cambridge Biomedical Campus. Visit postdoc jobs for related roles.

🧠What research areas does this position cover at University of Cambridge?

Focus on cell-type-selective gene expression in neuronal and glial systems, integrating long-read transcriptomics with RNA-targeted therapeutics for neurodegenerative disease biology. Part of interdisciplinary programme. Browse clinical research jobs.
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