Research Associate

Job Details

Research Associate

Job Summary

The Jurynec Lab (Department of Orthopaedics, www.juryneclab.org) is looking for a highly motived and independent Post Doctoral Research Fellow to be part of a multidisciplinary team studying the genetics of osteoarthritis. The lab uses human genetics, bioinformatics, molecular biology, and animal models to understand the factors that contribute to the onset and progression of osteoarthritis.

The Jurynec Lab has identified over 100 candidate gene variants that segregate with osteoarthritis in large pedigrees. We are analyzing candidate gene functions in tissue culture and generating mice the harbor human disease alleles to understand the contribution of these genes to the osteoarthritis phenotype. Analyses include CRISPR/Cas9 genome editing in mouse, scRNA-seq, spatial profiling, WES/WGS, and tissue culture. The candidate should be prepared to analyze gene function in vivo and preform genetic and chemical screens in vitro to identify potential therapeutics. The lab is funded by the NIH and foundation grants.

The applicant will be responsible for leading independent projects under the guidance of the PI. These studies include performing experiments with zebrafish, mice, and tissue culture. The applicant will also be responsible for the maintenance and breeding of zebrafish and mice.

Responsibilities

1. Performs and directs specialized and complex lab tests, experiments and surgical procedures for studies.

2. Assists the Principal Investigator in the design, implementation and performance of new protocols and procedures as well as the modification of existing techniques.

3. Reviews scientific journals, abstracts and other literature for information concerning experimental procedures.

4. Makes advanced statistical calculations, analyzes data and prepares reports summarizing research results.

5. Operates complex and highly specialized laboratory and surgical instruments and equipment. Instructs others in their use.

6. Maintains a log of supplies used in procedures.

7. May supervise, train and review the work of laboratory personnel.

8. May prepare equipment and rooms for studies.

9. May assist with preparing budgets.

Problem Solving

The Post Doc assists in the development of research protocols and designs. Modifies and implement procedures. Records and interprets research results. The incumbent works independently, under the general supervision of most senior laboratory personnel. Work may include training and supervising other laboratory personnel, who may refer sensitive or unusual situations to the incumbent. Problems that cannot be resolved by the incumbent will be referred to the most senior Lab personnel.

Minimum Qualifications

PhD or BS with 5+ years of experience for qualifications

Preferences

Work Environment and Level of Frequency that may be required:

Nearly Continuously: Laboratory environment.

Often: Exposure to animals, hazards (includes a variety of physical conditions, such as proximity to moving mechanical parts, moving vehicles, electrical current, working on scaffolding and high places, or exposure to chemicals).

Seldom:

Physical Requirements and Level of Frequency that may be required

Nearly Continuously: Hearing, listening, talking.

Often: Repetitive hand motion (such as typing), walking, standing, sitting.

Seldom: Bending, reaching overhead.

Special Instructions

Requisition Number: PRN44114B

Full Time or Part Time? Full Time

Work Schedule Summary: M-F

Department: 00269 - Orthopedic Surgery Operations

Location: Campus

Pay Rate Range: 55K-70K

Close Date: 4/26/2026

Open Until Filled: